Aripiprazole - Abilify

ryanc97 said:
Well, that assumes patients have no minds of their own and cannot evaluate what is said to them.

By advice I mean perspectives.
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The forum rules do not allow asking for or giving medical advice

See this in the additional notes on the No medical advice rule:

4. Do not attempt to diagnose or recommend treatments to others
...but they may not diagnose or recommend treatments to each other, nor request such diagnoses or recommendations
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You may not request or offer suggested treatments, including suggesting changing dosages or stopping prescribed medication.
 
As many patients anecdotally report that the effects of Aripiprazole/Abilify do wear off after some time, I wondered if there's any comments in scientific literature or even just in talks or other oublic statements about that from the Drs who prescribe this medication.

I know that in Germany, Austria and the U.S. there are at least some Drs who prescribe Low-Dose-Aripiprazole for ME, but I never heard anyone of them talking about this despite it being a seemingly pretty common experience among patients.

So is there any acknowledgment of these experience among treating Drs. and/or researchers? Especially now that they're conducting this new study on the subject in Germany, it would be important to examine this phenomenon as well.
 
Silip said:
As many patients anecdotally report that the effects of Aripiprazole/Abilify do wear off after some time, I wondered if there's any comments in scientific literature or even just in talks or other oublic statements about that from the Drs who prescribe this medication.
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A doctor I have been seeing, who has treated ME/CFS for a quite a while, asked me if it "wore off". That's as anectodal as it gets.

I couldn't answer the question because I did not know if it worked in the first place. It motivated me to stop it and see what happens. The result is: absolutely nothing. Maybe I sleep a bit better since (I found it quite activating even at low doses, but without actually giving me more leeway for PEM). I was at quite a high dose (3mg).
 
Silip said:
So is there any acknowledgment of these experience among treating Drs. and/or researchers? Especially now that they're conducting this new study on the subject in Germany, it would be important to examine this phenomenon as well.
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Extremely anecdotal: To date, I have not tried LDA, but did see a doctor who recommended it and had a number of other patients taking it. Some time back, when he first mentioned it, I asked him about the potential for the drug to stop working (if indeed it did anything at all) and he was confident that with a sufficiently slow and cautious approach this could be avoided. For a number of reasons, I declined to try it at that time. A year later it was mentioned again, but apparently his experience had changed as he then stated that it "frequently" only works for a limited time. His recommendation had shifted to memantine.
 
DHagen said:
Extremely anecdotal: To date, I have not tried LDA, but did see a doctor who recommended it and had a number of other patients taking it. Some time back, when he first mentioned it, I asked him about the potential for the drug to stop working (if indeed it did anything at all) and he was confident that with a sufficiently slow and cautious approach this could be avoided. For a number of reasons, I declined to try it at that time. A year later it was mentioned again, but apparently his experience had changed as he then stated that it "frequently" only works for a limited time. His recommendation had shifted to memantine.
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It pooped out then tried a mini break of two months but it didnt work as the first time (wonderfull effects, im severe and i could eat with my family in a sofa, watch tv, work for two hours and above all did 1500 steps a day).
I want to try rxulti to see if it works with that molecule.
 
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