B12/Folic Acid and D3/K2 Supplementation

Jonathan Edwards said:
Yes of course, but what has that to do with the discussion?
If levels are low and there are recognised clinical features of low B12 supplementation is needed.
But the original post mentioned normal levels.
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I was perhaps being pernickety, but I interpreted your statement as intending a general principle that B12 should never be supplemented if current levels are within normal levels, whereas there is the exception if you have good reason to anticipate supplementation is necessary to prevent the individual going into deficit then supplementation is appropriate though current levels are within a normal range.
 
Milo said:
What do you mean by teenage spots? Is it a British slang?
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No, it means what it says. Lots of teenagers get spots/zits/acne when they reach puberty. For most people the problem wears off by the time they are about 18 - 20. Mine did slightly improve but they never went away completely. It's embarrassing to have teenage spots at 30 or 40 or 50.
 
Arnie Pye said:
Anyone who wants to inject themselves with vitamin B12 can find out how and where to buy the necessary ampoules, syringes, needles etc from the Pernicious Anaemia Society forum which can be found here :

https://healthunlocked.com/pasoc

You have to join Healthunlocked to read their many forums. It's free.

You can't buy ampoules of Vitamin B12 in the UK, because anything which must be injected is prescription only, even vitamins. But there are no laws preventing people from importing it from France and Germany.



I had levels of B12 which were within the reference range. And my level wasn't even low in range. But I had a lot of symptoms which seemed to tie in with B12 deficiency. I started supplementing methylcobalamin (not cyanocobalamin) and the "teenage" spots I'd had for decades disappeared, and the eczema I'd had since I was about 10 improved by about 90%. Both the spots and the eczema got worse for a few weeks before getting better than they had been since before the conditions developed in the first place. My B12 level is now well over the range, and if I allow it to drop I get the spots and the eczema back.

I have tried to find the research that must have been done at one time to set the reference ranges for B12 and other nutrients but I've never been able to find it.
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The big metabolic studies would have picked up B12 deficiency so it seems that none of the participants had it. Also, B12 deficiency results in pernicious anemia so, if deficiency was relevant, there would be a lot of people presenting with anemia - they're not.
 
Kiristar said:
So I've finally seen a reputable consultant and he wants to prescribe
A b12,
B LDN
C aciclovir
I nearly fainted at the private prescription quote so want to make a case for the GP. Even if I self find this first batch I can't going forward long term.

Has anyone in the UK been able to Persuade GP to prescribe and get LDN or aciclovir funded on the NHS? I'm housebound so less bothered about the b12 as can't make it to the surgery to get jabbed weekly anyway and my b12 was always comfortably in range so difficult to argue)

If so what research papers / articles were most useful has there been a LDN trial yet. I am not good at succinctly explaining the medical theory of why this is a good strategy as my memory is so poor and I get totally stressed out even having to interact with medical professionals after past difficult experiences.
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I'd be interested to know why B12 was prescribed. The reference test was Methyl Malonic Acid, which increases when you're deficient in B12, but even the standard B12 tests should be OK.
 
Discussion moved from the long covid in the media thread

A male relative of ours, in his mid 30s, tested positive for Covid 19 Sat 19 March. Fully vaccinated, all three. Was very poorly for nearly a week, dreadful cough and feeling dreadful. After clearing the virus, then pretty exhausted. The similarities to my wife's ME/CFS pretty marked. At this point now, he is significantly better, with cough progressively improving. Still runs out of energy very quickly, which is no big surprise.

Had a chest x-ray, results not back yet.

Blood test apparently shows a very low level of folic acid - I don't know the actual reading. Is this likely to be a consequence of the covid? Or is it more likely coincidental, something that may have been brewing anyway? Or are there any known links with low folic acid and covid?
 
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Barry said:
A male relative of ours, in his mid 30s, tested positive for Covid 19 Sat 19 March. Fully vaccinated, all three. Was very poorly for nearly a week, dreadful cough and feeling dreadful. After clearing the virus, then pretty exhausted. The similarities to my wife's ME/CFS pretty marked. At this point now, he is significantly better, with cough progressively improving. Still runs out of energy very quickly, which is no big surprise.

Had a chest x-ray, results not back yet.

Blood test apparently shows a very low level of folic acid - I don't know the actual reading. Is this likely to be a consequence of the covid? Or is it more likely coincidental, something that may have been brewing anyway? Or are there any known links with low folic acid and covid?
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https://pubmed.ncbi.nlm.nih.gov/1887065/

Low folate status and immune function
Has vit D been checked too?
 
Barry said:
His doctor is pretty good I think, so I imagine it would have been included, but I can check.
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There is also a form of anemia linked to inflammation - common in chronic illness but also post infection .
How are iron levels ?
See thread
 
Barry said:
Blood test apparently shows a very low level of folic acid - I don't know the actual reading. Is this likely to be a consequence of the covid? Or is it more likely coincidental, something that may have been brewing anyway? Or are there any known links with low folic acid and covid?
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Folate is found in foods that a lot of people don't eat enough of, such has fruit/vegetables/whole grains/legumes. In observational studies males typically eat less of these foods than females, and it's easy to not get enough through diet alone. At the same time a folate deficiency can be masked by adequate/high B12 which is found in meat and dairy, which especially men tend to get enough of, and thus can go unnoticed. Folate is also water soluble and not stored particularly well in the body so if he was low (doesn't have to have been deficient) before becoming ill and has changed his diet due to being ill that can also contribute. And as already mentioned, being ill can increase the body's need for some nutrients.
 
Barry said:
Blood test apparently shows a very low level of folic acid - I don't know the actual reading. Is this likely to be a consequence of the covid? Or is it more likely coincidental, something that may have been brewing anyway? Or are there any known links with low folic acid and covid?
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If he had been ill and not eating much that might be relevant to a low folate level but I doubt it has anything to do with the Covid, or vice versa. We have just had our second Covid after three jabs and it is pretty draining - now nearly three weeks in.

I don't think all the stuff about anaemia and vitamins and chronic infection are relevant to an acute viral infection of this sort.
 
merged thread
Cyanocobalin 1000mcg without nasty stuff?

My doctor wants me to be on this but can anyone recommend one I can buy in the UK that doesn't have maltodextrin etc.?

A liquid would be ideal.
 
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I do not appear to suffer from a B12 deficiency, at least taking more does not improve things, and I would appear to have too much iron (inferred from my ferritin level). It is something I considered a 'while' back.
 
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