B12/Folic Acid and D3/K2 Supplementation

I’ve never supplemented vit d with the goal of improving me/cfs. Just with the goal of supplying adequate levels to my body since i dont get sunshine and try to protect against Ostheoperosis.

I don’t think this changes anything for those like me?
 
What is interesting is that I started taking vitamin D3 25 years ago after testing low, and ever since then I started feeling 'viral' all the time. I was fine before that :unsure:
 
What is interesting is that I started taking vitamin D3 25 years ago after testing low, and ever since then I started feeling 'viral' all the time. I was fine before that :unsure:
Interesting. I have had a similar experience.
About 20 years ago my doctor told me my Vit D levels were ridiculously low. I was told to take vit D supplements. The supplements, made my ME worse. Terrible brain fog, flu like feeling. So I gave up and figured maybe I was meant to have low Vit D levels.
I can't tolerate sunlight either though.
 
Date: December 30, 2025

Source: Vanderbilt University Medical Center

Why your vitamin D supplements might not be working

Summary: A randomized trial from Vanderbilt-Ingram Cancer Center reveals that magnesium may be the missing key to keeping vitamin D levels in balance. The study found that magnesium raised vitamin D in people who were deficient while dialing it down in those with overly high levels—suggesting a powerful regulating effect. This could help explain why vitamin D supplements don’t work the same way for everyone and why past studies linking vitamin D to cancer and heart disease have produced mixed results.
 
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