Source: Medically Unexplained Symptoms [Book] pp 141-157
Date: December 2, 2020
URL:
https://link.springer.com/book/10.1007/978-3-030-59181-6 https://link.springer.com/chapter/10.1007/978-3-030-59181-6_8
Fibromyalgia and Chronic Fatigue Syndrome
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Robert W. Baloh - Department of Neurology, University of California, Los Angeles, USA
Abstract
Fibromyalgia is generally considered a pain disorder, but most patients have additional symptoms, most commonly fatigue, insomnia and dizziness.
Chronic fatigue syndrome and fibromyalgia overlap in symptoms and are associated with a variety of psychophysiological disorders, including depression, anxiety and migraine.
Patients with fibromyalgia have central sensitization to pain which can be traced to several factors including genetic variants, prior exposure to pain and stressful life events.
Although many people believe that chronic fatigue syndrome is caused by a viral infection, post-viral activation of the immune system or primary immune system dysfunction, to date there is no convincing evidence for any of these disease mechanisms.
Large outbreaks of chronic fatigue syndrome in the UK and USA had features consistent with mass psychogenic illness, including a marked female predominance and the lack of objective neurological and laboratory findings.
Keywords: Fibromyalgia, Chronic fatigue syndrome, Fibrositis, Tender points, Repetitive strain injury (RSI), Neuromyasthenia, Epstein-Barr virus, Myalgic encephalomyelitis, Chronic fatigue immune dysfunction syndrome