Ken Ware - Neurophysics therapy

[Arfmeister]

There has been a lot of talk about anaerobic thresholds but do we have any good evidence for people with ME/CFS going above their threshold or for it to have anything to do with symptoms?

I have read a lot about ME CFS patients going above anaerobic threshold to cause symptoms and PEM-crashes. I could not find a publication at the moment, but I have had different exchanges with PEM-researcher Todd Davenport on the topic.

But I’m mostly going off by my own symptoms and measurements. Also discussed in this post in thread 'Lactic acid, lactate in ME/CFS'
https://www.s4me.info/threads/lactic-acid-lactate-in-me-cfs.44969/post-662992

As I understand: PEM would be caused by crossing the anaerobic threshold : Glycolysis outpacing mitochondrial oxidation

• Pyruvate ⇒ lactate
• Lactate accumulates in blood when the exertion intensity > lactate threshold