The findings that vaccination against SARS-CoV-2 does not protect against some of the post-acute outcomes of COVID-19 should not obscure the fact that vaccination remains an important protective factor against these outcomes at the population level, since the best way to prevent those outcomes is to prevent SARS-CoV-2 infection in the first place. This is also the case in those ≥ 60 years-old.23 However, our results highlight that some post-acute outcomes of SARS-CoV-2 (and notably long-COVID presentations) are likely to persist even after successful vaccination of the population, so long as breakthrough infections occur. These findings thus help in determining the necessary service provision. They also underline the urgency to identify other preventive or curative interventions to mitigate the impact of such COVID-19 sequelae.
That's a pretty important finding to support advocacy for ongoing research into Long Covid i.e. we know that vaccination doesn't entirely prevent breakthrough Covid-19 infections, and this study suggests breakthrough infections have about the same chance of causing Long Covid as Covid-19 infections in the unvaccinated. @SNT Gatchaman
(The findings about the lack of a big impact of vaccination in older people was sobering.)