Low temperature

I'd say a TSH of 3 is a bit too high. In Germany, the limits were changed some years ago. Now everything > 2.5 microU/ml is deemed as hypothyroidism, if I remember correctly. I also found 3,1 as upper limit. But to me, ft3 and ft4 look decent.

Edit: You could think about substituting folate; "active B12" is confusing. I prefer holo-transcobalamin or other metabolic products, e.g. homocysteine (but not alone).
 
Inara said:
I'd say a TSH of 3 is a bit too high. In Germany, the limits were changed some years ago. Now everything > 2.5 microU/ml is deemed as hypothyroidism, if I remember correctly. I also found 3,1 as upper limit. But to me, ft3 and ft4 look decent.

Edit: You could think about substituting folate; "active B12" is confusing. I prefer holo-transcobalamin or other metabolic products, e.g. homocysteine (but not alone).
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Thank you - that prompted further checking and yes it appears that internationally TSH levels above 2.5 can be regarded as evidence of hypothyroidism.

I've also discovered that at least one person with an internet page considers rT3 levels above 15 to be abnormal.

I have yet to do any serious digging (i.e. enough to understand) about folate levels. * so as I have some knocking about I'll just try it for a few months or until the bottle runs out and see if that makes any difference. I've been unable to find any reference ranges for it I can make sense of.

ETA - it also seems that a hs CRP above 3 suggests I may at "severe" risk of a cardiac event, which is odd as according to the doctors notes that came with these results he suggests that it may be a risk to my liver - and suggests giving up alcohol (they were told I don't drink), giving up smoking (ditto) and exercise (they were told I had ME), and the little status indicator on their website gives a green for it :grumpy:
 
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Wonko said:
I have yet to do any serious digging (i.e. enough to understand) about folate levels. * so as I have some knocking about I'll just try it for a few months or until the bottle runs out and see if that makes any difference. I've been unable to find any reference ranges for it I can make sense of.
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I would take "active folic acid" - is that folate? Ohhhh :bear: I take MTHF. Folate is one suggestion by the Charité ("things you can try").

My feeling was that the CRP wasn't too low (but not too high either...well). Probably it's not important?
 
Inara said:
I would take "active folic acid" - is that folate? Ohhhh :bear: I take MTHF. Folate is one suggestion by the Charité ("things you can try").

My feeling was that the CRP wasn't too low (but not too high either...well). Probably it's not important?
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I'm taking it, along with the ferritin result as just an indication of "inflammation", something I already knew about but didn't have any numbers.

It is, unfortunately, probably time to prod my GP tho.
 
Wonko said:
35.6C, shortly after getting up.

@Dechi - as it's a forehead thermometer, presumably using some form of program to arrive at a core temp based on what it sees on the surface, I would think even slight surface cooling, such as from being in a cold environment or sweating, could significantly alter it's calculations, and lead to a low result. So far I'm not seeing stuff that suggests it's defective, unfortunately I have no heat sources with a definite known temperature within this things range, or at all for that matter (apparently kettles don't boil at precisely 100C for some reason).

So it's either a case of buy a mercury thermometer to check it against (Yum yum) or test it on someone else next time I meet someone whose both healthy and non ancient, at around 3pm, (fairly sure these days just wandering up to someone and measuring their temperature is assault lol)
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Good luck with finding a mercury thermometer. Digital ones seem to have replaced these. No doubt a H&S issue
 
Amw66 said:
Good luck with finding a mercury thermometer. Digital ones seem to have replaced these. No doubt a H&S issue
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That seems a bit unreasonable, given that the non mercury ones seem to suffer from the small flaw of not actually being very good at measuring temperature (according to amazon reviews anyway).

But yes, I had noticed that they no longer seem to be available, even as "collectors" items on ebay.
 
Wonko said:
Depending on the results I will decide on what treatment to try, most thyroid things can be bought online, I'm actually much more concerned about blood tests to calibrate treatment, especially if they need to be done in the morning. They will be a major problem if needed frequently.

I am not actually expecting my GP to do anything helpful even if it comes back with a TSH of 23, IMO it's unlikely she will acknowledge understanding many of the other test results ;)

re hashimoto's, I thought the delay was caused by them not actually testing for the right things? If, if, I get results that suggest hashimoto's then I will look up the appropriate treatment and source.

Don't get me wrong, I'm not hoping for any thyroid problems, but I am looking for an explanation to several things, one of which is why NDT had such a profound effect on several secondary symptoms. It would be "simpler" if the tests showed something, if not, I can strike it off the list.

I'm fed up, and have been for some time, of operating in the dark, because my GP will not do any "basic" testing, I want some numbers so I can see what "might" be helpful to try and address - probably a complete waste of time, effort and money but....
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Unfortunately if things are within " normal ranges", GPs will not look any further. Testing is set up to look for specifics ( usually near end states), and misses associations. It seems illogical that nothing is done when repeated tests show you sliding towards one scenario - until you hit the out of range parameter. Clinical observation seems to have died a death for many aspects of conditions.

Make a case if you have other established symptoms - ( the weirdest one for hypothryroidism being loss of outer third of eyebrows - i would love to know the mechanism behind that). Having a low energy condition will/ should impact on the interpretation of test results- you are clearly not functioning in any " normal capacity", wny are you being compared to "normal" people if there is a well known HPA axis issue.
Thyroid hormones can activate the uncoupling of OXPHOS via mechanisms involving inner membrane proteins an lipids- there are links between mitochondrial proton leak mechanisms, ROS production and thyroid status

metabolic dysfunction could explain many issues where low ATP and Mg affects cellular pump action ( needed for TH formation.. glucuronidation action to get it out of cells ......) You also need specific compounds to make the different thyroid hormones - TSH needs B12, zinc. T4 needs iodine, vit B2 and vit C, T4 to T3 is a selenium dependent process, and T3 needs vit D and vit A to activate cell receptor. Significant deficiencies in these compounds may effect parts of the process.

I have not done biology since 2nd year in school ( I preferred the joy of crashing ticker tape experiments in physics), but some of this seems a bit obvious? Or am I simply fulfilling that neurotic woman role again?
 
At the moment I'm just trying to build a picture of what the various results could suggest, symptom matching with my life etc., with a largely non functional brain that has the same retention capability as a sieve.

One that does strike me is that have had bone pain for at least 20 years, which is apparently a symptom of low D3, mainly in my lower legs and forearms, so I "may" have been low for a while.

The ferritin thing, my reading suggests ferritin should be inside cells, and only tends to leave when the cell is damaged or dies, could this be related to the the stiff red blood cell thing I've seen knocking about recently, RBC's getting damaged coz they are too stiff to get where they should. Iron is allegedly a neurotoxin, could this be responsible, at least partially, for my cognitive issues, motor control issues etc.

More...that I can't remember right now, I just remember these were more things.

ETA - I'm not expecting anyone to answer, anything, I'm just musing, on the record lol

ETA again - I'm also seeing a link, but only in some symptom lists, between very low D3 (and maybe very high ferritin, think so but, as I said above, my memory..) and insulin resistance. It never made sense to me why I would become a type 2 diabetic, my weight, whilst higher than it should be was never seriously heavy, no family history, never really eaten high sugar, sweets, cake etc. my only major carb intakes were bread, potatoes and rice, and then not typically in excess.

@Amw66 video doesn't play :(
 
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Amw66 said:
Link to page with video. First video near start has GGT / Ferritin info.
There is also a very good vitamin D video on this website.
http://www.thefatemperor.com/blog/
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Some, but only some, of what he says matches conclusions I came to several years ago, mainly the stuff about diet. But even when I've had success, dropping meds and using diet alone, my GP has been adamant that my approach (of reducing insulin resistance by reducing my intake insulin provoking foods, that eventually this would restore insulin sensitivity and at the very least lead to a reduction in my weight, which should help in its own right), is totally wrong, and that I should instead take tablets to increase insulin production by various parts of my body.
 
Wonko said:
Some, but only some, of what he says matches conclusions I came to several years ago, mainly the stuff about diet. But even when I've had success, dropping meds and using diet alone, my GP has been adamant that my approach (of reducing insulin resistance by reducing my intake insulin provoking foods, that eventually this would restore insulin sensitivity and at the very least lead to a reduction in my weight, which should help in its own right), is totally wrong, and that I should instead take tablets to increase insulin production by various parts of my body.
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Unfortunate it' s a bit like this illness- goes against what they have been told for so long
 
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