Perturbation of effector and regulatory T cell subsets in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (2019) Karhan, Unutmaz et al

Done and waiting for an answer

 

OK Derya Unutmaz answered, he is checking it and will get back. He also said about posting soon a revised version of the paper. This table (Supplemental table 2 which i could not find in the paper) is very important i think, because it shows the features used for the machine learning algorithm used to classify between ME patients and controls.

 

https://twitter.com/user/status/1230598565485043726

 

Is low cd8, cd8 lymphopenia a frequent finding in me/cfs?

 

A number of studies have found no difference between ME/CFS and controls for basic T cell subsets like CD8.

 

So if a patient would have chronically low cd8 count (for years), what would you think about that?

 

Not very much. Counts of cells in blood vary a lot.

 

Hi butter, we have a few threads on this subject. It seems some pwME CD8 counts are high, while others are low. It varies. Mine are below normal range.

 

same here! any differences in severity?

 

Not really, but I do experience more viral re-activations.

I have a friend with lower numbers than mine but never feels 'viral', she has a lot of allergies.

 

MAIT cell activation and dynamics associated with COVID-19 disease severity

https://immunology.sciencemag.org/content/5/51/eabe1670.full