animal model

  1. Andy

    Improvement Effects of Myelophil on Symptoms of Chronic Fatigue Syndrome in a Reserpine-Induced Mouse Model, 2021, Song et al

    Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is associated with various symptoms, such as depression, pain, and fatigue. To date, the pathological mechanisms and therapeutics remain uncertain. The purpose of this study was to investigate the effect of myelophil (MYP)...
    • Andy
    • Thread
    • animal model astragali radix astragalus astralagus me/cfs salvia south korea tcm treatment
    • Replies: 6
    • Forum: ME/CFS research
  2. Andy

    [Electroacupuncture improves cognitive function by inhibiting NF-κB activity in rats with chronic fatigue syndrome], 2021, Feng et al

    Objective: To observe the effect of electroacupuncture (EA) on the expression of NF-κB p65 in hippocampus and the morphology of hippocampus in rats with chronic fatigue syndrome (CFS), so as to explore its mechanism in improving cognitive dysfunction of CFS. Methods: Forty-eight SD rats were...
    • Andy
    • Thread
    • acupressure acupuncture animal model china me/cfs treatment
    • Replies: 4
    • Forum: Other treatments
  3. Andy

    Moderate, Intermittent Voluntary Exercise in a Model of Gulf War Illness Improves Cognitive and Mood Function..., 2021, Kodali et al

    Full title: Moderate, Intermittent Voluntary Exercise in a Model of Gulf War Illness Improves Cognitive and Mood Function with Alleviation of Activated Microglia and Astrocytes, and Enhanced Neurogenesis in the Hippocampus Highlights • Moderate, intermittent voluntary exercise improved...
  4. Andy

    Pioglitazone improves skeletal muscle functions in reserpine-induced fibromyalgia rat model, 2021, Hassan et al

    Abstract Background Fibromyalgia (FM) is characterized by musculoskeletal pain, fatigue, sleep and memory disturbance. There is no definitive cure yet for FM-related health problems. Peroxisome proliferator-activated receptor’s (PPAR’s) activation is associated with insulin sensitisation and...
  5. Andy

    A proprietary herbal drug Young Yum Pill ameliorates chronic fatigue syndrome in mice, 2021, Yin et al

    Abstract Background: Chronic fatigue syndrome (CFS) is a complex disease with few effective and safe therapies. Young Yum Pill (YYP), a proprietary herbal drug, has been used to relieve CFS-like symptoms. The pharmacological basis of this application of YYP is unknown. Purpose: This study...
    • Andy
    • Thread
    • animal model china me/cfs tcm treatment
    • Replies: 5
    • Forum: ME/CFS research
  6. Hutan

    Nonhuman primate models for EBV infection, 2014, Wang

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713193/ Dr. Fred Wang, Harvard Medical School, Brigham & Women’s Hospital, Medicine and Microbiology & Immunobiology Abstract Epstein-Barr virus (EBV) is a human herpesvirus that infects nearly all humans by adulthood and is associated with a...
  7. Dolphin

    Oxidative stress caused by a dysregulated Wnt/β-catenin signalling pathway... abnormal placenta ... in pregnant mice with CFS, 2020, Zhao et al

    https://www.cambridge.org/core/journals/zygote/article/oxidative-stress-caused-by-a-dysregulated-wntcatenin-signalling-pathway-is-involved-in-abnormal-placenta-formation-in-pregnant-mice-with-chronic-fatigue-syndrome/732B77AB5F851B50AC2886C97DE5D7F2 Oxidative stress caused by a dysregulated...
  8. Andy

    Pre-print: Innate immune signaling & sex differences contribute to [..] impairment, neuroinflammation, & mitochondrial rewiring in [GWI], 2020, Bryant

    Full title: Innate immune signaling and sex differences contribute to neurocognitive impairment, neuroinflammation, and mitochondrial rewiring in a mouse model of Gulf War illness https://www.biorxiv.org/content/10.1101/2020.08.28.271833v1
  9. Sly Saint

    Polish zoo to give elephants cannabis extract for stress relief

    full article here https://notesfrompoland.com/2020/08/24/polish-zoo-to-give-elephants-cannabis-for-stress-relief/ (I hope they have plenty of snacks available for the elephants during their treatment.)
  10. Andy

    Effects of a high fat diet on gut microbiome dysbiosis in a mouse model of Gulf War Illness, 2020, Kuhn et al

    Open access, https://www.nature.com/articles/s41598-020-66833-w
  11. Andy

    Protective Effect of Hemin Against Experimental Chronic Fatigue Syndrome in Mice: Possible Role of Neurotransmitters, 2020, Kumar et al

    Mouse model = mice they have exhausted through over exercising. Therefore this is of dubious use to us. Paywall, https://link.springer.com/article/10.1007/s12640-020-00231-y Open access PDF paper, https://sci-hub.tw/10.1007/s12640-020-00231-y
    • Andy
    • Thread
    • 2020 animal model kumar me/cfs mice paper
    • Replies: 7
    • Forum: ME/CFS research
  12. Dolphin

    Homeostatic disturbance of thermoregulatory functions in rats with chronic fatigue, 2020, Li

    https://www.sciencedirect.com/science/article/pii/S0168010220301577
    • Dolphin
    • Thread
    • 2020 animal model danxi li me/cfs paper thermoregulation
    • Replies: 2
    • Forum: ME/CFS research
  13. Dolphin

    Targeting sirtuin activity with nicotinamide riboside reduces neuroinflammation in a GWI mouse model, 2020, Joshi et al

    NeuroToxicology Available online 25 April 2020
  14. Andy

    Metabolomics in Psychiatric Disorders: What We Learn from Animal Models, 2020, Humer et al

    Open access, https://www.mdpi.com/2218-1989/10/2/72
  15. Andy

    An Adrenalectomy Mouse Model Reflecting Clinical Features for Chronic Fatigue Syndrome, 2020, Lee et al

    Another dubious mouse model, this time from Korea. Open access, https://www.mdpi.com/2218-273X/10/1/71
  16. Andy

    Neuroinflammation, Oxidative Stress, and Neurogenesis in a Mouse Model of [CFS], and the Treatment with Kampo Medicine, 2020, He et al

    Another dubious mouse model of CFS from Japan. Open access, https://www.jstage.jst.go.jp/article/bpb/43/1/43_b19-00616/_html/-char/en
    • Andy
    • Thread
    • 2020 animal model herbal medicine japan me/cfs neuroinflammation paper
    • Replies: 1
    • Forum: ME/CFS research
  17. Simone

    Animal Models of ME/CFS

    I’m wondering if anyone is aware of any appropriate mouse models of ME/CFS? I’m familiar with the Japanese model of putting the mice/rats in a layer of water, but that’s really a model of chronic stress, not ME/CFS. Are there any others?
  18. Andy

    GI neuroimmune disruption contributes to Gulf War Illness (2019)

    https://www.sciencedaily.com/releases/2019/02/190221141506.htm
  19. Hutan

    Go Slow - a CFS-like disease of dogs

    I'm interested in diseases of animals that might be similar to ME/CFS, as I think it is likely that humans are not the only mammals to suffer from this disease or collection of diseases. This morning on the radio (Radio NZ) I heard about a disease called 'Go Slow' which has been affecting dogs...
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