long covid

Randomized controlled double-blind trial of methylprednisolone versus placebo in patients with post-COVID-19 syndrome and cognitive deficits: study protocol of the post-corona-virus immune treatment (PoCoVIT) trial Abstract Introduction Post-COVID-19 Syndrome (PCS) includes neurological...

Diagnostic and clinical management of non-obstructive myocardial ischemia in patients with long Covid-19 syndrome and new-onset chest pain: Design and rationale of the long Covid-19 INOCA trial Abstract Background Beyond the respiratory symptoms of acute Infection from the SARS-CoV-2 virus...

Incidence of long COVID-related consultations in family medicine in Switzerland: a cross-sectional study within the Sentinella network Abstract STUDY AIMS: The initial prevalence estimates of long COVID exhibited significant heterogeneity. In Switzerland, early findings estimated a 39–53%...

VSL#3® supplementation improves fatigue in long COVID: results from the DELong#3 randomized placebo-controlled trial Background Long COVID is frequently characterized by persistent fatigue and impaired quality of life. Increasing evidence suggests that gut microbiota dysbiosis and immune...

This short film (6 1/2 minutes) is available on YouTube. For blind or visually impaired viewers there's an audio track that includes descriptions of the movements. An extract from the YouTube summary: Disclaimer, also from the summary: More information, including names and bios for the...

Neuroanatomical subtypes of Long COVID reveal distinct cognitive profiles alongside longitudinal brain changes Abstract Background: Long COVID is characterized by persistent symptoms following SARS-CoV-2 infection, including cognitive deficits among its most disabling manifestations...

Estimating Impact of SARS-CoV-2 Infection on Health-Related Quality of Life Among Persons Aged 8 Years and Older, August 2020–July 2022 Abstract Background: Severe COVID-19 results in substantial economic burden and impacts quality of life. Assessing how mild COVID-19 impacts health...

Losartan and prednisolone for post-COVID syndrome and cardiac inflammation: a randomized, double-blind, placebo-controlled trial Abstract Persistent cardiac symptoms are common in post-COVID syndrome, even without structural heart disease. Evidence implicates immune dysregulation...

Beyond the Counted Cohort: The Long COVID Shadow Population in the United States A Two-Arm Convergent Burden Estimate and a Hypothesis on Spike-Mediated Immune Failure Abstract Background. Current United States surveillance recognises only the self-reported Long COVID cohort (approximately...

Now published, see post #5. Preprint below: An Open-Label Feasibility Study of Remdesivir in Long COVID: Results from the ERASE LC Trial Objective Treatment of acute COVID-19 with anti-viral and immunomodulator medications demonstrates a reduced risk of long-term outcomes. To date...

Peripheral blood cytokines during early and post-acute stages of SARS-CoV-2 infection are associated with disease severity and long-term symptoms Abstract Background: U.S. Veterans experience a high burden of COVID-19; characterizing immune responses associated with COVID-19 outcomes could...

Persistent cytolytic CD8+ T cells recognize SARS-CoV-2 and herpesvirus epitopes in long COVID Highlights • Combinatorial tetramer deep-profiling of viral-specific T cells in long COVID (LC) • LC features more cytolytic CD8+ T cells against SARS-CoV-2, CMV, and EBV • Females with LC exhibit...

Sex and occupational differences in long COVID prevalence among healthcare workers: a multicentre registry-based study in three Spanish hospitals Abstract Aims To estimate the prevalence of long COVID identified through hospital registry data and examine associated occupational and...

Acute symptoms and subsequent post-acute symptoms following COVID-19 vaccination: A Danish population-based study Objectives Acute symptoms are common following COVID-19 vaccination, yet it remains unclear if these reactions can manifest or progress into non-specific symptoms (e.g., headache...

Pathogen effects on the brain: the case of SARS-CoV-2 spike protein and neuro COVID Theoharides, Theoharis C.; Papadopoulou, Paraskevi Abstract Many patients develop cognitive and neuropsychiatric issues after viral infections, but the mechanisms are not well understood. A case in point is...

The Impact of Long COVID on the Female Reproductive System: A Narrative Review Abstract Long COVID affects multiple organ systems and disproportionately affects women, raising concerns about reproductive health. This updated narrative review summarizes evidence from PubMed, Scopus, and Web of...

In the newest study by Wüst and colleagues, they have both a Long Covid and a pre pandemic ME/CFS group. Both groups fulfill CCC, so experience PEM. My question: is there any research into severe Long Covid (e.g. at least 12 months and disabling) that does not also fulfill ME/CFS criteria? I...

Prevalence, trends, and correlates of long COVID in mainland China after the policy shift: findings from two cross-sectional surveys Abstract Background The long-term consequences of the Chinese COVID-19 wave in 2022 remain unknown. To clarify the health outcomes of COVID-19 survivors after...

The Burden of Long-COVID-19 Among Pediatric Subjects: A Systematic Review and Meta-Analysis Abstract Background/Objectives: There is wide variability in the available estimates on the burden of Long-COVID (LC), both among adults and children. Preliminary evidence suggests that this...

Evolutionary Predictors of Post-COVID Syndrome Abstract Objectives: To analyze evolutionary predictors of post-COVID syndrome (PCS). Methods: This Cohort study was conducted from April 2021 to December 2023. PCS persistence was defined as a score of ≥2 points on the post-COVID-19 Functional...