long covid

Now published - link here ******************** The remote diet intervention to reduce Long COVID symptoms trial (ReDIRECT): protocol for a randomised controlled trial to determine the effectiveness and cost-effectiveness of a remotely delivered supported weight management programme for people...

Full title: From human herpes virus-6 reactivation to autoimmune reactivity against tight junctions and neuronal antigens, to inflammation, depression, and chronic fatigue syndrome due to Long COVID Abstract Inflammation and autoimmune responses contribute to the pathophysiology of Long COVID...

Abstract Objective: To estimate the number of people in Australia with long COVID by age group, and the associated medium term productivity and economic losses. Study design: Modelling study: a susceptible–exposed–infected–recovered (SEIR) model to estimate the number of people with long COVID...

Abstract Long COVID is a debilitating, multisystemic illness following a SARS-CoV-2 infection whose duration may be indefinite. Over four years into the pandemic, little knowledge has been generated from clinical trials. We analyzed the information available on ClinicalTrials.gov, and found...

Job advert on DWP site. Not difficult to see how they view Long Covid. Summary Be responsible for planning, reviewing and renegotiating programmes of care to promote health gains, maximise independence, recovery and reablement within a defined caseload in conjunction with the Long COVID Tier 3...

Abstract Background Omicron variant impacts populations with its rapid contagiousness, and part of patients suffered from persistent symptoms termed as long COVID. The molecular and immune mechanisms of this currently dominant global variant leading to long COVID remain unclear, due to long...

Discovered this new website in English launching a treatment programme for Long Covid patients. It's by Marianne Svanevik, a physiotherapist who has treated ME for years with GET and CBT. She's a proponent of Lightning Process and I remember she was furious on the journal for Norwegian...

Abstract Background: Long coronavirus disease (COVID; LC) affects millions of people worldwide. The exact mechanisms which result in a broad, undulating and detrimental symptom profile remain unknown. Blood biomarkers associated with LC have been described; however, consensus on these remains...

A quest to manage CYP with ME/CFS and long covid under one MDT service – evaluation of a regional centre for CYP ME/CFS and long covid services Abstract Objectives Long Covid (LC) is a debilitating condition seen both in adults and CYP since COVID-19 pandemic.1 The similarities between LC and...

Modifiable lifestyle factors and the risk of post-COVID-19 multisystem sequelae, hospitalization, and death Wang, Yunhe; Su, Binbin; Alcalde-Herraiz, Marta; Barclay, Nicola L.; Tian, Yaohua; Li, Chunxiao; Wareham, Nicholas J.; Paredes, Roger; Xie, Junqing; Prieto-Alhambra, Daniel Effective...

Abstract Background: The term “Long COVID” is commonly used to describe persisting symptoms after acute COVID‑19. Until now, proposed mechanisms for the explanation of Long COVID have not related quantitative measurements to basic laws. In this work, a common framework for the Long COVID...

Abstract Long COVID is a common sequela of SARS-CoV-2 infection. Data from numerous scientific studies indicate that long COVID involves a complex interaction between pathophysiological processes. Long COVID may involve the development of new diagnosable health conditions and exacerbation of...

Influential studies from the VA St. Louis take a broad view of long Covid. Not every expert agrees with the approach. https://undark.org/2024/07/25/long-covid-clash-of-definition-study-design/

Identification of SARS-CoV-2 Persistent Infectious Epithelial Syndrome (SPIES) as a Novel Disease Entity using Clinical, Histologic, and RNA Programmatic Data Thomas Wallach, Ahmed Soliman, John Agboola, Shagun Sharma, Lais Araujo Coelho, Meredith Pittman, Christos Chatzinakos, Sergios-Orestis...

Key Points Question Does prevalence of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)–like illness differ between individuals with an acute infection–like index illness who are COVID-19 positive or negative? Findings In this cohort study of 4378 participants, the weighted...

Bioinformatic analysis predicts the regulatory function of noncoding SNPs associated with Long COVID-19 syndrome Maiti, Amit K. Long or Post COVID-19 is a condition of collected symptoms persisted after recovery from COVID-19. Host genetic factors play a crucial role in developing Long...

Abstract SARS-CoV-2-contributes to sickness and death in COVID-19 patients partly by inducing a hyper-proinflammatory immune response in the host airway. This hyper-proinflammatory state involves activation of signaling by NFκB, and unexpectedly, ENaC, the epithelial sodium channel...

Brief Summary The trial will test if two repurposed HIV antivirals can reduce symptom burden in adult participants with Long Covid compared to placebo. Viral infection and viral reactivation have been documented in Long Covid. Participants will be randomly allocated to receive antivirals, TDF...

Sleep and circadian rhythm alterations in myalgic encephalomyelitis/chronic fatigue syndrome and post-COVID fatigue syndrome and its association with cardiovascular risk factors: A prospective cohort study Abstract This study aimed to investigate circadian rhythm manifestations in Myalgic...

A Long COVID Definition A Chronic, Systemic Disease State with Profound Consequences (Consensus Study Report) National Academies of Sciences, Engineering, and Medicine. 2024. A Long COVID Definition: A Chronic, Systemic Disease State with Profound Consequences. Washington, DC: The National...