long covid

An Open-Label Feasibility Study of Remdesivir in Long COVID: Results from the ERASE LC Trial Objective Treatment of acute COVID-19 with anti-viral and immunomodulator medications demonstrates a reduced risk of long-term outcomes. To date, remdesivir, an intravenous (IV) antiviral that...

Peripheral blood cytokines during early and post-acute stages of SARS-CoV-2 infection are associated with disease severity and long-term symptoms Abstract Background: U.S. Veterans experience a high burden of COVID-19; characterizing immune responses associated with COVID-19 outcomes could...

Persistent cytolytic CD8+ T cells recognize SARS-CoV-2 and herpesvirus epitopes in long COVID Highlights • Combinatorial tetramer deep-profiling of viral-specific T cells in long COVID (LC) • LC features more cytolytic CD8+ T cells against SARS-CoV-2, CMV, and EBV • Females with LC exhibit...

Sex and occupational differences in long COVID prevalence among healthcare workers: a multicentre registry-based study in three Spanish hospitals Abstract Aims To estimate the prevalence of long COVID identified through hospital registry data and examine associated occupational and...

Acute symptoms and subsequent post-acute symptoms following COVID-19 vaccination: A Danish population-based study Objectives Acute symptoms are common following COVID-19 vaccination, yet it remains unclear if these reactions can manifest or progress into non-specific symptoms (e.g., headache...

Pathogen effects on the brain: the case of SARS-CoV-2 spike protein and neuro COVID Theoharides, Theoharis C.; Papadopoulou, Paraskevi Abstract Many patients develop cognitive and neuropsychiatric issues after viral infections, but the mechanisms are not well understood. A case in point is...

The Impact of Long COVID on the Female Reproductive System: A Narrative Review Abstract Long COVID affects multiple organ systems and disproportionately affects women, raising concerns about reproductive health. This updated narrative review summarizes evidence from PubMed, Scopus, and Web of...

In the newest study by Wüst and colleagues, they have both a Long Covid and a pre pandemic ME/CFS group. Both groups fulfill CCC, so experience PEM. My question: is there any research into severe Long Covid (e.g. at least 12 months and disabling) that does not also fulfill ME/CFS criteria? I...

Prevalence, trends, and correlates of long COVID in mainland China after the policy shift: findings from two cross-sectional surveys Abstract Background The long-term consequences of the Chinese COVID-19 wave in 2022 remain unknown. To clarify the health outcomes of COVID-19 survivors after...

The Burden of Long-COVID-19 Among Pediatric Subjects: A Systematic Review and Meta-Analysis Abstract Background/Objectives: There is wide variability in the available estimates on the burden of Long-COVID (LC), both among adults and children. Preliminary evidence suggests that this...

Evolutionary Predictors of Post-COVID Syndrome Abstract Objectives: To analyze evolutionary predictors of post-COVID syndrome (PCS). Methods: This Cohort study was conducted from April 2021 to December 2023. PCS persistence was defined as a score of ≥2 points on the post-COVID-19 Functional...

Anxiety-Depressive Disorders in 200 Patients with Post-COVID-19 Syndrome: Prevalence and Predictors from a Cross-Sectional Study Abstract Background and Objectives: Recovering from COVID-19 does not always imply a full return to health and may lead to the development of post-COVID-19...

Reliability and Validity of the Simple Qi Deficiency Score in Patients with Post-COVID-19 Condition Abstract Background and Objectives: Persistent COVID-19 sequelae, often referred to as “long COVID”, still constitute a major global medical challenge. In particular, general fatigue is the...

Neuroretinal Alterations in Persistent COVID-19: A Two-Year OCT Follow-Up Abstract Background/Objectives: To evaluate long-term neuroretinal changes in patients with persistent COVID-19 (PC) versus asymptomatic controls, using optical coherence tomography (OCT) over a two-year follow-up...

Post-COVID-19 Condition in Swiss Healthcare: Disparities in Access, Delays in Care, and Patient Burden Abstract Background: Post-COVID-19 Condition (PCC) causes persistent multisystem symptoms, reduced quality of life, and high healthcare needs. Data on patient experiences in Switzerland are...

A call to educate: counteracting enacted stigma in children with long COVID Yonts, Alexandra B. No abstract, here the first couple paragraphs: By some accounts, Long COVID (LC) is now one of the most common chronic childhood illnesses in the United States, affecting between 1 million and 8...

Emerging trends in post-COVID immune dysregulation: a narrative review Abstract Background: Long coronavirus disease (COVID), or post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, is a multi-system condition associated with persistent immune...

Pacing and energy management with digital tools for conditions with chronic fatigue: What we know so far in ME/CFS and Long COVID There is no abstract, so instead this is the last section: Bottom line Pacing works best when it is personalised, conservative, and supported by timely feedback...

664. Attitudes about COVID and Community Engagement with Patients (ACCEPt): Global Survey Reveals the Ongoing Impact of Long COVID-19 on Medically Vulnerable Populations, Five Years On Abstract Background COVID-19 continues to disproportionately impact medically vulnerable populations. To...

Characterization and Validation of EHR Computable Phenotypes for Long COVID Using Patient-Reported Symptoms: Insights from the Nationwide RECOVER Program Abstract Objective Long COVID (LC) remains poorly understood, and there is a critical need for advanced computational tools to better...