treatment

  1. Sly Saint

    Efficacy and tolerability of an endogenous metabolic modulator (AXA1125) in fatigue-predominant long COVID: a single-centre, double-blind, randomised

    Efficacy and tolerability of an endogenous metabolic modulator (AXA1125) in fatigue-predominant long COVID: a single-centre, double-blind, randomised controlled phase 2a pilot study Lucy E.M. Finnigan Mark Philip Cassar Margaret James Koziel Joel Pradines Hanan Lamlum Karim Azer et al...
  2. M

    Low dose Naltrexone - How might it work biologically in ME/CFS?

    LDN Tlr4 inhibition explanation If LDN works via inhibit glia tlr4, does that mean tlr4 is being activated in the first place? So what was activating? Or can inhibiting tlr4 inhibit the common pathways of other signals? For example il1. Tldr, if glia is activated by il1, can inhibit tlr4...
  3. Andy

    Low-level tragus stimulation improves autoantibody-induced hyperadrenergic postural tachycardia syndrome in rabbits 2023 Guo et al

    Background Recent studies have demonstrated that antiadrenergic autoantibodies are involved in the pathophysiology of postural orthostatic tachycardia syndrome (POTS). Objective The purpose of this study was to test the hypothesis that transcutaneous low-level tragus stimulation (LLTS)...
  4. Dolphin

    Non-Pharmacological Therapies for Post-Viral Syndromes, Including Long COVID: A Systematic Review, 2023, Singh Chandan et al

    Free fulltext: https://www.mdpi.com/1660-4601/20/4/3477 Non-Pharmacological Therapies for Post-Viral Syndromes, Including Long COVID: A Systematic Review by by Joht Singh Chandan 1,*,Kirsty R. Brown 1,2,Nikita Simms-Williams 1,Nasir Z. Bashir 3,Jenny Camaradou 4,Dominic Heining 5,Grace M...
  5. Andy

    Four-year follow-up on fatigue and sleep quality of a three-armed partly randomized controlled study in breast cancer survivors... 2023 Kröz et al

    Full title: Four-year follow-up on fatigue and sleep quality of a three-armed partly randomized controlled study in breast cancer survivors with cancer-related fatigue Abstract Cancer-related fatigue (CRF) is a frequent long-term symptom in non-metastasized breast cancer patients (BC). This...
  6. J

    Case series: Maraviroc and pravastatin as a therapeutic option to treat long COVID/Post-acute sequelae of COVID (PASC), Patterson et al 2023

    https://www.frontiersin.org/articles/10.3389/fmed.2023.1122529/full Post-acute sequelae of COVID (PASC), or long COVID, is a multisystem complication of SARS-CoV-2 infection that continues to debilitate millions worldwide thus highlighting the public health importance of identifying effective...
  7. Trish

    The Draft Report by the Institute..[IQWiG] Does Not Provide Any Evidence That GET and CBT are Safe and Effective treatments for ME/CFS, 2023, Vink et

    The Draft Report by the Institute for Quality and Efficiency in Healthcare Does Not Provide Any Evidence That Graded Exercise Therapy and Cognitive Behavioral Therapy Are Safe and Effective Treatments for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome by Mark Vink and Alexandra Vink-Niese...
  8. Hutan

    Stem cells as treatments

    American Cryosystem Corporation is running a trial "Treatment of Long COVID Utilizing Autologous Stem Cells" The details are here on Clinical Trials. Both the treatment arm and the placebo arm will have fat cells removed by liposuction. Later the treatment arm will have 150 million cells of...
  9. Mij

    Old Antipsychotic Drugs May Offer New Option to Treat Type 2 Diabetes

    Summary: Diphenylbutylpiperidines (DPBPs), a older class of antipsychotic medications can effectively be repurposed to help treat type 2 diabetes, a new study reports. The mechanism Ussher and his team turned their attention to is succinyl CoA:3-ketoacid CoA transferase (SCOT), an enzyme...
  10. J

    Temelimab

    Temelimab #3, l'évolution de mon état après 2 injections Translation: Temelimab #3, the evolution of my condition after 2 injections
  11. Hutan

    Reduced Pro-Inflammatory Cytokines after Eight Weeks of Low-Dose Naltrexone for Fibromyalgia, 2017, Parkitny and Younger

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489802/ Open access Abstract Fibromyalgia (FM) is a complex, multi-symptom condition that predominantly affects women. The majority of those affected are unlikely to gain significant symptomatic control from the few treatments that are approved for...
  12. Hutan

    The use of low-dose naltrexone (LDN) as a novel anti-inflammatory treatment for chronic pain, 2014, Younger, Parkitny and McLain

    https://link.springer.com/article/10.1007/s10067-014-2517-2 Open access Abstract Low-dose naltrexone (LDN) has been demonstrated to reduce symptom severity in conditions such as fibromyalgia, Crohn’s disease, multiple sclerosis, and complex regional pain syndrome. We review the evidence that...
  13. Mij

    Efficacy and Safety Study of Efgartigimod in Adults With Post-COVID-19 POTS (POTS)

    https://clinicaltrials.gov/ct2/show/study/NCT05633407?term=efgartigimod&cond=POTS+-+Postural+Orthostatic+Tachycardia+Syndrome&draw=2&rank
  14. Andy

    Can different degrees of resistance training improve mood states in patients with fibromyalgia? A randomized controlled trial 2022 Vilarino et al

    The purpose of this study was to look at the effects of low and high intensity resistance training (RT) on the mood states of fibromyalgia patients (FM). A total of 69 women participated in the study, with 31 healthy women serving as control group (HC), and 28 women diagnosed with FM being...
  15. Dolphin

    POTS and Pregnancy: A Review of Literature and Recommendations for Evaluation and Treatment (has section on CFS), 2022, Morgan

    Free full text: https://www.dovepress.com/pots-and-pregnancy-a-review-of-literature-and-recommendations-for-eval-peer-reviewed-fulltext-article-IJWH REVIEW POTS and Pregnancy: A Review of Literature and Recommendations for Evaluation and Treatment Authors Morgan K , Smith A, Blitshteyn S...
  16. Andy

    Effects of a Telerehabilitation Program in Women with Fibromyalgia at 6-Month Follow-Up: Secondary Analysis... 2022 Hernando-Garijo et al

    Abstract (1) Background: Telerehabilitation allows health professionals to monitor patients without face-to-face contact. The objective was to analyze the effects of a telerehabilitation program based on aerobic exercise in women with fibromyalgia at 6-month follow-up. (2) Methods...
  17. Andy

    Clinical effects of wasabi extract containing 6-MSITC on myalgic encephalomyelitis/chronic fatigue syndrome: an open-label trial 2022 Oka et al

    Abstract Background Wasabi (Eutrema japonicum) is a common pungent spice used in Japan. 6-Methylsulfinylhexyl isothiocyanate (6-MSITC) found in the rhizome of wasabi has been shown to have anti-inflammatory and antioxidant effects, as well as improve neuroinflammation and memory. Therefore, we...
  18. Andy

    Effects of l-Arginine Plus Vit C on Physical Performance, Endothelial Function, and Persistent Fatigue in Adults with Long COVID 2022 Tosato et al

    Full title: Effects of l-Arginine Plus Vitamin C Supplementation on Physical Performance, Endothelial Function, and Persistent Fatigue in Adults with Long COVID: A Single-Blind Randomized Controlled Trial Abstract Long COVID, a condition characterized by symptom and/or sign persistence...
  19. hellytheelephant

    Is There Anyone (UK) On The Forum who Is Prescribed Medical Marijuana?

    I really wonder how Drs in can give prescriptions for Oramoph and Tramadol but not medical marijuana.... Does anyone have any thoughts? https://www.independent.co.uk/life-style/health-and-families/multiple-sclerosis-symptoms-hereditary-cause-b2239253.html
  20. Trish

    Blood clot drug totally ineffective as post-Covid treatment, research finds. Results from UK-wide trials on anticoagulant Apixaban

    Financial Times article: Blood clot drug totally ineffective as post-Covid treatment, research finds Results from UK-wide trials on anticoagulant Apixaban set to change protocols around the world A drug to reduce blood clots, widely prescribed to Covid-19 patients after discharge from hospital...
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