treatment

  1. Andy

    Low-Dose Hydrocortisone for Treatment of Chronic Fatigue Syndrome - A Randomized Controlled Trial, 1998, McKenzie et al

    Abstract Context.— Chronic fatigue syndrome (CFS) is associated with a dysregulated hypothalamic–pituitary adrenal axis and hypocortisolemia. Objective.— To evaluate the efficacy and safety of low-dose oral hydrocortisone as a treatment for CFS. Design.— A randomized, placebo-controlled...
  2. LarsSG

    High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: randomized, phase 2, crossover trial 2022 Hansen et al

    Preprint and final publication threads merged Final publication abstract further down the thread here Abstract Background: Post COVID-19 condition (PCC) is defined as symptoms lasting more than 12 weeks after developing COVID-19. Evidence of mitochondrial dysfunction has been reported in...
  3. Mij

    Diagnosis and treatment of orthostatic hypotension, 2022, Wouter Wieling, MD et al

    Summary Orthostatic hypotension is an unusually large decrease in blood pressure on standing that increases the risk of adverse outcomes even when asymptomatic. Improvements in haemodynamic profiling with continuous blood pressure measurements have uncovered four major subtypes: initial...
  4. D

    Closed Fred Friedberg (University of Stonybrook) Hydrogen Rich Water; Heart rate variability biofeedback in CFS

    via healthrising https://www.healthrising.org/blog/2020/04/29/hydrogen-rich-water-chronic-fatigue-fibromyalgia-friedberg/
  5. Sly Saint

    Australia: NSW Agency for Clinical Innovation: Exercise and long COVID

    Review pdf Question(s) Is exercise helpful in individuals with long COVID? Is post-exertional symptom exacerbation a risk in long COVID? https://aci.health.nsw.gov.au/__data/assets/pdf_file/0010/735562/Evidence-Check-Exercise-and-long-COVID.pdf
  6. Andy

    What psychological interventions are effective for the management of (PPS)? A systematic review and meta-analysis, 2022, Swainston et al

    Full title: What psychological interventions are effective for the management of persistent physical symptoms (PPS)? A systematic review and meta-analysis Abstract Objectives Presentation of persistent physical symptoms is associated with increased health care utilization, yet clinical...
  7. Andy

    Animal Models for Neuroinflammation and Potential Treatment Methods, 2022, Tamura et al

    [This seems to be only very tenuously about ME/CFS] Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic disease of unknown etiology and without effective treatment options. The onset of ME/CFS is often associated with neuroinflammation following bacterial or...
  8. Andy

    Patient-led integrated CBT for management of long COVID with comorbid depression and anxiety in primary care - A case study, 2022, Skilbeck

    Abstract Objective Long COVID affects approximately ten-percent of people following post-acute Coronavirus infection. Long COVID is a complex, multisystemic recent illness. Therefore, there are currently no unitary guidelines on its management. The UK national guidelines currently recommended...
  9. Sly Saint

    Hyperbaric oxygen therapy improves neurocognitive functions & symptoms of post-COVID condition: randomized controlled trial, 2022, Zilberman-Itskovich

    Abstract Post-COVID-19 condition refers to a range of persisting physical, neurocognitive, and neuropsychological symptoms after SARS-CoV-2 infection. The mechanism can be related to brain tissue pathology caused by virus invasion or indirectly by neuroinflammation and hypercoagulability. This...
  10. B

    Rapid improvement in severe long COVID following perispinal etanercept, 2022, Tobinick et al

    https://www.tandfonline.com/doi/abs/10.1080/03007995.2022.2096351 This study aimed to describe the neurological improvements in a patient with severe long COVID brain dysfunction following perispinal etanercept administration. Perispinal administration of etanercept, a novel method designed to...
  11. Andy

    Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration, 2018, Ryu et al

    Abstract Activation of innate immunity and deposition of blood-derived fibrin in the central nervous system (CNS) occur in autoimmune and neurodegenerative diseases, including multiple sclerosis (MS) and Alzheimer’s disease (AD). However, the mechanisms that link disruption of the blood–brain...
  12. Sly Saint

    Oxaloacetate Treatment For Mental And Physical Fatigue In (ME/CFS) and Long-COVID fatigue patients, 2022, Cash and Kaufman

    full title: Oxaloacetate Treatment For Mental And Physical Fatigue In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long-COVID fatigue patients: a non-randomized controlled clinical trial Abstract Background There is no approved pharmaceutical intervention for Myalgic...
  13. Sly Saint

    United Kingdom: NHS East Kent Hospitals University - CFS/ME

    Chronic Fatigue Syndrome (CFS) / Myalgic Encephalopathy (ME) and Physiotherapy: Information leaflet pdf link here...
  14. Mij

    Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults, 2022, Sophia Liu, PhD et al

    Abstract Importance Aging is associated with a decline in mitochondrial function and reduced exercise capacity. Urolithin A is a natural gut microbiome–derived food metabolite that has been shown to stimulate mitophagy and improve muscle function in older animals and to induce mitochondrial...
  15. Sly Saint

    Guidelines in practice: Draw on expert opinion to optimise care for long COVID

    Dr Harsha Master, Dr Ashish Chaudhry, Dr Nicholas Gall, Dr Louise Newson, Dr Sarah Glynne, and Dr Paul Glynne present their experiences of diagnosing, managing, and referring patients with long COVID and associated conditions...
  16. J

    Yoga is effective in treating symptoms of Gulf War illness: A randomized clinical trial Hayley,Younger et al 2021

    Yoga!—Jared Younger https://www.sciencedirect.com/science/article/abs/pii/S0022395620310839 Abstract Many Veterans of the 1990–1991 Gulf War report symptoms of Gulf War Illness, a condition involving numerous chronic symptoms including pain, fatigue, and mood/cognition symptoms. Little is known...
  17. Mij

    Implantable neurostimulators for neurogenic orthostatic hypotension: the wave of the future? ... updates on ... autonomic research, 2022, Miglis et al

    Full title: Implantable neurostimulators for neurogenic orthostatic hypotension: the wave of the future? and Other updates on recent autonomic research, 2022, Mitchell G. Miglis et al Multiple system atrophy (MSA) is the most aggressive neurodegenerative disease of alpha-synuclein deposition...
  18. Andy

    Epipharyngeal Abrasive Therapy (EAT) Has Potential as a Novel Method for Long COVID Treatment, 2022, Imai et al

    Abstract COVID-19 often causes sequelae after initial recovery, referred to collectively as long COVID. Long COVID is considered to be caused by the persistence of chronic inflammation after acute COVID-19 infection. We found that all long COVID patients had residual inflammation in the...
  19. Andy

    Electroacupuncture at BL15 attenuates chronic fatigue syndrome by downregulating iNOS/NO signaling in C57BL/6 mice, 2022, Yang et al

    Abstract Chronic fatigue syndrome (CFS) has a high incidence due to the increased pressure of daily life and work in modern society. Our previous clinical studies have found the effects of electroacupuncture (EA) on CFS patients, however, the mechanism of EA on CFS is still unknown. In this...
  20. Unable

    Massage therapies including Bowen Therapy and myofascial release

    The Perrin technique is discussed here: Perrin Technique ***** I came across this article this morning. The link was from a canine massage therapist, but the article is about human massage. Apparently, it is a myth that massage disperses lactic acid from muscles after exercise, and that in...
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