A logistic regression analysis of risk factors in ME/CFS pathogenesis. Lacerda et al. 2019

Another thing to be careful of is the old association vs causation error.

The association of virus episodes prior to ME onset might be seen as causal, but another way to look at it is that the same unknown etiology might cause both immune failure as an early symptom and ME onset as a later symptom.

At this stage we dont know either way. 2c

 

I wonder is anything interesting among these, perhaps particularly from Trudie Chalder?
https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-019-1468-2/peer-review

 

I see a statistician was recruited as a reviewer and was paid a “small honorarium”. Might be worthwhile for other journals to do this also.

 

A statistical reviewer suggested some other means of analysis (I can’t recall the details now). Prior immunizations in the six months prior to onset dropped out as a risk factor with the new analysis.

 

This study used the Reeves et al (2005) criteria which give a prevalence rate of 2.54% and which are really bad.

 

"A logistic regression analysis of risk factors in ME/CFS pathogenesis" (Nov 2019).

Has data on lots of items in table 2 (see image for list) in an unadjusted form of simple numbers & %s in case you're interested in looking at data on your pet theories

https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-019-1468-2



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