ME/CFS Science Blog
Senior Member (Voting Rights)
Even though this region falls just below the significance threshold, the credible set lies entirely inside the SOX6 gene, making it quite likely that this is the relevant one.
The 3D domain only includes C11orf58 as another protein coding gene. The FLAMES algorithm was also quite confident about SOX6 being the relevant gene for this signal.
The other chromatin analyses didn't reveal much.
For the eQTL I tested more than 2000 datasets but only 2 reached PP.H4 and they were only weak signals.
The Phewas showed a couple of genetic studies that share a signal here including overal health rating, brain-white matter MRI and miserableness.
The 3D domain only includes C11orf58 as another protein coding gene. The FLAMES algorithm was also quite confident about SOX6 being the relevant gene for this signal.
The other chromatin analyses didn't reveal much.
For the eQTL I tested more than 2000 datasets but only 2 reached PP.H4 and they were only weak signals.
The Phewas showed a couple of genetic studies that share a signal here including overal health rating, brain-white matter MRI and miserableness.