ME/CFS Science Blog
Senior Member (Voting Rights)
Perhaps not the most interesting locus but it does have a signal just below the significance threshold (p = 1.9 × 10⁻⁷) in DecodeME.
The credible set lies in the gene ZNF644 which is also the most likely candidate.
In the Hi-C on the 3D-folding BARHL was in the same domain and had multiple contacts to the credible interval, so this is the second most likely causal gene.
The chromatin data and eQTL didn't much interesting findings but the phewas found a clear colocalization with HDL cholesterol and triglyceride and brain connectivity measures.
The credible set lies in the gene ZNF644 which is also the most likely candidate.
In the Hi-C on the 3D-folding BARHL was in the same domain and had multiple contacts to the credible interval, so this is the second most likely causal gene.
The chromatin data and eQTL didn't much interesting findings but the phewas found a clear colocalization with HDL cholesterol and triglyceride and brain connectivity measures.