The biology of coronavirus COVID-19 - including research and treatments

Discussion in 'Epidemics (including Covid-19, not Long Covid)' started by Trish, Mar 12, 2020.

  1. ahimsa

    ahimsa Senior Member (Voting Rights)

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    I have one friend who told me he believed something like this. He saw a video on Facebook and warned me (this was way back in March) that getting any of the COVID vaccines would make things worse for everyone all over the world.

    But I think it was by a different person than the one you mentioned.

    The "scientist" behind the video my friend saw is Geert Vanden Bossche. Turns out he is "board certified in Veterinary Virology, Microbiology and Animal Hygiene and hasn’t published a research paper since 1995" (quote from https://vaxopedia.org/2021/03/14/who-is-geert-vanden-bossche/).

    I don't claim to understand all the scientific details but his theories have been debunked on snopes and many other sites (searching for debunk bossche should find a lot of them).

    Edit: missing word
     
    Last edited: Jul 6, 2021
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  2. Wits_End

    Wits_End Senior Member (Voting Rights)

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    Yes, I don't understand it either. The UK Government has spent the last year telling us that we need to wear face masks to protect others from being infected with Covid, yet now suddenly it's fine for us to choose not to wear them. Almost as if the masks were protecting us rather than others. Or alternatively as if we could stop bothering about anyone but ourselves all of a sudden - we can do exactly what we want, and everyone else can take a running jump. It makes no sense whatsoever.
     
  3. Mithriel

    Mithriel Senior Member (Voting Rights)

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    It makes sense when you realise they are trying to sell a product. UK faced crisis, crisis solved.

    Everything is back to normal, vaccination, which government did really well, pat on the back, has worked, covid is no more deadly than flu or pneumonia, ignoring the demographics of that, and you can go out and spend money just like before.

    Wearing a mask would keep reminding everyone there is a serious danger out there.

    I was intrigued as well as worried so I have been looking at the newspapers and BBC. Everything they are saying is true but in a way we are used to in the ME community. There are graphs showing average deaths and hospitalisations comparing then and now which make everything look rosy. In Scotland and the North of England which are the highest in Europe the hospital situation is dreadful. They are opening covid wards again and the staff are exhausted trying to cope.

    A quote on the BBC says that we cannot prevent people dying from covid by letting others die of cancer and other things. Yet as Jonathan Edwards pointed out it is having doctors being overwhelmed by covid patients that is stopping the cancer clinics.

    We will have to learn to live with covid but not by going back to 2019 life but by forming a new normal. Making changes to how we live will not only help with covid but with the next epidemic which is coming. In my lifetime, I have seen attitudes change as people forgot how to live with infectious disease. New generations who never experienced them must relearn how to protect themselves and their families.

    Government has an opportunity here but they are throwing it away.
     
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  4. shak8

    shak8 Senior Member (Voting Rights)

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    In May, our county in California had an average of 2.7 postives per 100k population. After the June reopening and with the mask mandate removed (except for the suggested nonvaccinated wearing masks), the case rate has increased to 6 per 100k.

    This leaves always a pool of over 700 people potentially passing on the virus, not to mention double or triple that number of asymptomatics spreading the virus.

    There's at least 35% percent of adults not getting vaccinated and of course the children under 12 can't yet.
     
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  5. Jonathan Edwards

    Jonathan Edwards Senior Member (Voting Rights)

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    No, I think your analysis is right. A non-vaccinated person must be a better variant factory than the same person vaccinated. The idea of 'evolutionary pressure' is bogus. Mutation is inherent to the DNA and the host cell replication machinery. Pressure does not increase it. If there is competition between genetic variants then it can look as if there is evolutionary pressure but I see no evidence for any competition with Covid-129. 90% of UK cases are now delta variant not because delta has chased away alpha but just because it spreads faster. and alpha had almost died out with lockdown and the vaccine programme.
     
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  6. oldtimer

    oldtimer Senior Member (Voting Rights)

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    "Researchers have found what could be a secret weapon against new variants of COVID-19 – a type of drug related to a common blood thinner that’s effective at stopping the virus from binding with cells. QUT [Queensland University of Technology] researchers have been looking into how heparin sulphate (HS), which is in the same family as the blood-thinning drug Heparin, binds to the spike protein on the surface of the virus." https://www.theage.com.au/national/...-battling-covid-variants-20210706-p587cb.html

    The research has been published in the Computational and Structural Biotechnology Journal. https://www.sciencedirect.com/science/article/pii/S2001037021001835
     
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  7. Snow Leopard

    Snow Leopard Senior Member (Voting Rights)

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    This might be a disaster. Heparin sulphate does indeed bind to the spike protein, which I have previously mentioned, but I have proposed a similar mechanism for the thrombosis with thrombocytopenia syndrome, due to B-cell cocapture of PF4-Heparan sulfate-spike protein complexes.
     
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  8. Amw66

    Amw66 Senior Member (Voting Rights)

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    Is this similar to TTP ?
     
  9. Snow Leopard

    Snow Leopard Senior Member (Voting Rights)

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    Yes, that is what I'm suggesting.
     
  10. Amw66

    Amw66 Senior Member (Voting Rights)

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    Awful condition - 3 years ago friend's son was admitted to hospital feeling ill and died 8 days later. I had thought, wrongly, that it was hereditary.
     
  11. Snow Leopard

    Snow Leopard Senior Member (Voting Rights)

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    Actually, I was wrong, they have similar names, but TTP is apparently a different syndrome (despite having the same set of symptoms), and is associated with a different autoantibody (against ADAMTS13).

    There is a very rare genetic cause, but it only explains 1% of TTP cases, the rest are autoimmune syndromes.
     
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  12. Snow Leopard

    Snow Leopard Senior Member (Voting Rights)

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  13. Suffolkres

    Suffolkres Senior Member (Voting Rights)

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    Craig Robinson uploaded a file in the group: Dr Sarah Myhill.
    Dr Myhill has asked us to post this report by Evidence-based Medicine Consultancy Ltd, dated 26 May 2021 and with the title 'Urgent preliminary report of Yellow Card data up to 26th May 2021'
     

    Attached Files:

  14. Amw66

    Amw66 Senior Member (Voting Rights)

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  15. Yessica

    Yessica Senior Member (Voting Rights)

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    This article is from May 27, 2021. Not sure how much and how well science has evolved since then. Also other unknowns into play more now too.

    Can people vaccinated against COVID-19 still spread the coronavirus? | PBS NewsHour

    @ahimsa Hi :). Not sure if anything in this article is helpful to you regarding your post asking about this.
     
    Last edited: Jul 11, 2021
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  16. Yessica

    Yessica Senior Member (Voting Rights)

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    Another one. Doesn't go into much detail about transmission to others from vaccinated. Infectious disease specialist Lyssette Cardona, MD does answer other questions. Quotes are two of my areas of concern.

    Can Vaccinated People Transmit COVID-19 to Others? – Health Essentials from Cleveland Clinic

     
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  17. Yessica

    Yessica Senior Member (Voting Rights)

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    CDC Data Suggests Vaccinated Don’t Carry, Can’t Spread Virus

    https://www.msn.com/en-us/health/me...ed-don-t-carry-can-t-spread-virus/ar-BB1f8ofp

    Sigh. What she says is misleading. My bolding. (Paragraph breaks mine to make it more easily readable.)

    This article is from March 30, 2021. I'm posting because it shows a study and also because I wish such statements weren't made so definitely especially early on in these things because that's all most people pay attention too and remember.

    If it is a small percentage, those who are vulnerable need to know this, not be told that the vaccinated do not carry the virus. I know the reasons for her saying that is to encourage everyone to get vaccinated, etc, yet it is misleading and puts an extra burden (and danger) for those that are not well protected due to medical, medications and possibly age.

    Edit: Here more details of the study is given.

    CDC study shows single dose of Pfizer or Moderna Covid vaccines was 80% effective (cnbc.com)
     
    Last edited: Jul 11, 2021
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  18. Mithriel

    Mithriel Senior Member (Voting Rights)

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    They are worried about flu this winter as they know what to put in the vaccine each year because of what happens in the southern hemisphere but this year they did not get flu. It means the vaccine will be a guess.

    Surely carrying on with basic precautions like distancing and masks in crowded spaces is sensible because that could be spread by vaccinated people even if they do not spread flu.

    If someone is weakened by flu what is the chance of getting covid despite being vaccinated?
     
  19. Sid

    Sid Senior Member (Voting Rights)

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  20. mango

    mango Senior Member (Voting Rights)

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    Press release by Danderyd Hospital, Sweden:
    Antikroppar efter mild covid-19 håller i minst ett år och binder också den nya Delta-varianten
    https://www.ds.se/om-oss/press2#/pr...binder-ocksaa-den-nya-delta-varianten-3116980
     
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