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Interview with neuroimaging researcher Zack Shan



"What my research now is, we have these brain MRI findings. Can we combine with smart sensors and biomarkers? Eventually, what we find can apply to a real patient without MRI data. Because, for research, we can collect rich phenotype data, and we already have this rich phenotyping data for research purposes. We can apply it to a new, single patient with probably just one or two, let's say, smart sensor, or biomarker. You don't necessarily have to have the range. [...] For real live, or daily clinic, we can just use one or two modalities."

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"We have logged the dynamic brain blood flow, autonomic function, and neuroinflammation in ME/CFS. As a group, ME/CFS patients always show clear anomalies across these systems, yet none of these measures alone define the disease. So what that tells me is, ME/CFS is not a single disease, but it is a disease with different biological subtypes. "
 
Interview with neuroimaging researcher Zack Shan


Solve ME has posted a short description of the interview:

Inside the Brain, Clues to ME/CFS Subtypes
Solve ME said:
In this interview, Dr. Shan shares:
  • What his team is learning from brain scans and autonomic testing
  • Why biological subtypes may hold the key to future diagnosis and treatment
  • How real-world patterns in patients are shaping the next generation of ME/CFS research
  • What it means to truly listen to the patient voice in science
 
So what that tells me is, ME/CFS is not a single disease, but it is a disease with different biological subtypes.

Maybe.

Cancer has a wide range of forms, symptoms and signs, and causes (genetic, chemical, infectious, radiological), and different treatments. But all cancers have one thing in common – abnormal unregulated cell growth.
 
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