2021

  1. Sly Saint

    Video: COVID Long Haulers and the Connection to ME/CFS by Dr. Bateman

    In August 2021, Dr. Bateman delivered a didactic to Nurse Practitioners and Physician Assistants where she addressed post-acute sequelae of COVID-19 (PASC), Long Haul COVID, ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome), and orthostatic intolerance/dysautonomia. In this lecture...
  2. Mij

    OPTN is a host intrinsic restriction factor against neuroinvasive HSV-1 infection, 2021, Joshua Ames

    Abstract Fast-replicating neurotropic herpesviruses exemplified by herpes simplex virus-1 (HSV-1) naturally infect the central nervous system (CNS). However, most individuals intrinsically suppress the virus during a primary infection and preclude it from significantly damaging the CNS...
  3. Andy

    Long COVID: Distinction between Organ Damage and Deconditioning, 2021, Kersten et al

    Abstract (1) Background: Long COVID syndrome refers to long-term sequelae of the novel viral disease, which occur even in patients with initially mild disease courses. However, there is still little evidence of the actual organic consequences and their frequency, and there is no standardized...
  4. Sly Saint

    Long COVID and post-infective fatigue syndrome – a review, 2021, Sandler, Moss-Morris, Crawley, Knoop et al

    Abstract Fatigue is a dominant feature of both acute and convalescent COVID-19 (sometimes termed ‘long-COVID’), with up to 46% of patients reporting fatigue lasting weeks to months. The investigators of the international Collaborative on Fatigue Following Infection (COFFI) conducted a systematic...
  5. V

    Ganglionic Acetylcholine Receptor Antibodies in Postural Tachycardia Syndrome. Bryarly et al. 8/2021

    https://pubmed.ncbi.nlm.nih.gov/34484936/ Abstract Objective: Postural tachycardia syndrome (POTS), the most common form of dysautonomia, may be associated with autoimmunity in some cases. Autoantibodies against the ganglionic acetylcholine receptor (gAChR) have been reported in a minority of...
  6. Andy

    OMEGA AGM & Karl Morten - latest Biomedical Research into ME from Oxford, Sept 18th 2021, 2pm UK

    "THIS EVENT IS ONLINE ONLY. It will be held on Zoom, hosted by OMEGA. You will be sent a link to the meeting shortly before the start time to the email address you sign up with. This event is FREE. Any enquiries, please email enquire.omega@gmail.com. OMEGA is a support group for people with ME...
  7. Sly Saint

    Follow-Ups on Persistent Symptoms and Pulmonary Function Among Post-Acute COVID-19 Patients: A Systematic Review and Meta-Analysis, 2021, Long et al

    Objective: As the number of recovering COVID-19 patients increases worldwide, the persistence of symptoms and signs through the post-acute phase indicates an urgent need for prolonged follow-up care. To explore existing data about post-acute COVID-19 syndrome, this meta-analysis assesses the...
  8. MSEsperanza

    Cognitive Impairment After COVID-19. A Review on Objective Test Data (2021) Daroische et al.

    Daroische R, Hemminghyth MS, Eilertsen TH, Breitve MH, Chwiszczuk LJ. Cognitive Impairment After COVID-19. A Review on Objective Test Data. Front Neurol. 2021 Jul 29;12:699582. doi: 10.3389/fneur.2021.699582. PMID: 34393978; PMCID: PMC8357992. https://pubmed.ncbi.nlm.nih.gov/34393978/...
  9. Andy

    Porphyromonas gingivalis infection promotes mitochondrial dysfunction through Drp1-dependent mitochondrial fission in endothelial cells, 2021,Xu et al

    Abstract Porphyromonas gingivalis (P. gingivalis), a key pathogen in periodontitis, has been shown to accelerate the progression of atherosclerosis (AS). However, the definite mechanisms remain elusive. Emerging evidence supports an association between mitochondrial dysfunction and AS. In our...
  10. Andy

    Exercise performance in patients with post-acute sequelae of SARS-CoV-2 infection compared to patients with unexplained dyspnea, 2021, Alba et al

    Abstract Background Dyspnea and exercise intolerance are commonly reported post-acute sequelae of SARS-CoV-2 infection (PASC), but routine diagnostic testing is often normal. Cardiopulmonary exercise testing (CPET) offers comprehensive assessment of dyspnea to characterize pulmonary PASC...
  11. Andy

    Chronic Fatigue Syndrome and Cardiovascular Disease: JACC State-of-the-Art Review, 2021, Natelson et al

    Highlights • ME/CFS, a clinical entity of unknown etiology characterized by PEM, is easily diagnosed when following available guidelines. • Patients with ME/CFS typically have small hearts, low stroke volume, and low total blood volume, and some have OI. • More studies are needed to understand...
  12. Andy

    Disability Rights UK/Chronic Illness Inclusion evidence gathering survey on potential collaboration between different illness groups, closes 25th Sept

    This survey is part of a collaboration between Disability Rights UK and Chronic Illness Inclusion. The aim of this survey is to explore 1) Whether people with different energy-limiting health conditions and impairments are interested in working together on issues of social justice and...
  13. Nightsong

    'A life I can cope with'. An alternative model of cognitive behavioural therapy (CBT) for CFS/ME, Clark et al., 2021

    Abstract Objectives: This study aimed to explore the experience of cognitive behavioural therapy (CBT) aimed at better management of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME), rather than increasing activity. Design: This was a qualitative study using grounded theory...
  14. Dolphin

    Genetic study of T cell receptor (TCR) in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), 2021, Ueland (Masters thesis)

    From: Dr. Marc-Alexander Fluks Source: University of Oslo Date: May 18 and June 21, 2021 URL: https://www.duo.uio.no/bitstream/handle/10852/87105/7/Ueland_MasterThesis_2021.pdf Ref: https://www.mn.uio.no/ibv/studier/aktuelt/mastereksamen/var-2021/marthe%20ueland.html Genetic study of...
  15. Kalliope

    Acute Corticotropin-Releasing Factor Receptor Type 2 Agonism Result in Sustained Improvement in ME/CFS - Pereira, Bateman et al, 2021

    frontiers in Systems Neuroscience Acute Corticotropin-Releasing Factor Receptor Type 2 Agonism Result in Sustained Improvement in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome by Pereira, Bateman et al Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex...
  16. Kalliope

    The Atlantic: Long Covid is everyone's problem, 2021, Ed Yong

    Split from Possibility of ME or PVFS after COVID-19, Long Covid The Atlantic Long COVID Is Everyone's Problem by Ed Yong quote: One of the biggest misconceptions about long COVID is that it is entirely new. The SARS-CoV-2 coronavirus may have emerged in 2019, but many infections can lead to...
  17. Andy

    Editorial: Lancet: "Understanding long COVID: a modern medical challenge", 2021

    "As the COVID-19 pandemic continues, the need to understand and respond to long COVID is increasingly pressing. Symptoms such as persistent fatigue, breathlessness, brain fog, and depression could debilitate many millions of people globally. Yet very little is known about the condition. The term...
  18. Andy

    Sex-specific plasma lipid profiles of ME/CFS patients and their association with pain, fatigue, and cognitive symptoms, 2021, Nkiliza, Klimas et al

    Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex illness which disproportionally affects females. This illness is associated with immune and metabolic perturbations that may be influenced by lipid metabolism. We therefore hypothesized that plasma...
  19. Hoopoe

    Predictors of Nonseroconversion after SARS-CoV-2 Infection, 2021, Liu et al

    Predictors of Nonseroconversion after SARS-CoV-2 Infection https://wwwnc.cdc.gov/eid/article/27/9/21-1042_article ____________________ CDC study finds that 36% of COVID patients never make antibodies This has implications for prevalence studies of long covid that assume a lack of...
  20. Jonathan Edwards

    Guardian Article on NICE pause

    https://www.theguardian.com/society/2021/aug/30/withdrawal-planned-guidance-me-leaves-patients-distraught Natalie Grover seems to be getting nearer to understanding the problem, even if still a little way away. Some reasonable quotes from me. Some from Sharpe and Chalder as well.
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