2021

  1. Sly Saint

    CFS: A Case Report .. Diagnosing and Treatment Challenges and the Possibility of Jarisch–Herxheimer Reactions..., 2021, Straub and Powers

    Chronic Fatigue Syndrome: A Case Report Highlighting Diagnosing and Treatment Challenges and the Possibility of Jarisch–Herxheimer Reactions if High Infectious Loads Are Present Straub and Powers Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex multi-system...
  2. Wyva

    Brain–Immune Interactions as the Basis of Gulf War Illness: Clinical Assessment and Deployment Profile of (...), 2021, Steele, Klimas et al

    Abstract The Boston University-based Gulf War Illness Consortium (GWIC) is a multidisciplinary initiative developed to provide detailed understanding of brain and immune alterations that underlie Gulf War illness (GWI), the persistent multisymptom disorder associated with military service in...
  3. R

    100,000 Genomes Pilot on Rare-Disease Diagnosis in Health Care — Preliminary Report, 2021, Smedley et al.

    https://www.nejm.org/doi/full/10.1056/NEJMoa2035790 Abstract BACKGROUND The U.K. 100,000 Genomes Project is in the process of investigating the role of genome sequencing in patients with undiagnosed rare diseases after usual care and the alignment of this research with health care...
  4. Trish

    Insular cortex neurons encode and retrieve specific immune responses, 2021, Tamar Koren et al.

    https://www.cell.com/cell/pdf/S0092-8674(21)01223-X.pdf Research done in mice. Highlights Neuronal ensembles in the InsCtx are activated during peripheral inflammation Reactivation of these neurons is sufficient to retrieve peripheral inflammation These InsCtx neurons project to autonomic...
  5. Sly Saint

    Understanding The Molecular Changes of Post Exertional Malaise In ME/CFS, 2021, Elley

    Abstract: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating and often life-long condition affecting over 20,000 New Zealanders. Symptoms include muscle and joint pain, severe fatigue, unrefreshing sleep, hypersensitivity to light and sound, and cognitive dysfunction...
  6. Sly Saint

    How to make study documents clear and relevant: the impact of patient involvement, 2021, Jilka et al

    Abstract Background Patient and public involvement can improve study outcomes, but little data have been collected on why this might be. We investigated the impact of the Feasibility and Support to Timely Recruitment for Research (FAST-R) service, made up of trained patients and carers who...
  7. Samuel

    Early diagnostics of autoinflammatory disorders associated with post-viral CFS and cognitive impairments in chronic ... herpes, 2021, Nesterova et al

    vvv Source: Medical Immunology Vol 23, #4, pp 975-980 Date: July/August 2021 URL: https://www.mimmun.ru/mimmun/article/view/2439 https://www.mimmun.ru/mimmun/article/view/2439/1456 Early diagnostics of autoinflammatory disorders associated with post-viral chronic fatigue...
  8. J

    Use of whole genome sequencing to determine genetic basis of suspected mitochondrial disorders: cohort study, 2021, Schon et al.

    Posts moved from this thread: Trial of Long Covid treatment - AXA1125 from Axcella Therapeutics, 2021 ________________ Use of whole genome sequencing to determine genetic basis of suspected mitochondrial disorders: cohort study Abstract Objective To determine whether whole genome sequencing...
  9. Sly Saint

    Podcast: Episode 37: Finding Answers for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

    Opinionated Science Episode 37: Finding Answers for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Mesothelioma November 5, 2021 ME/CFS first 17 minutes...
  10. Andy

    Physical Activity, Fitness Level, Kinesiophobia, and Health-Related QoL in Patients with Rheumatic & Musculoskeletal Diseases, 2021, Courbalay et al

    Full title: Direct and Indirect Relationships Between Physical Activity, Fitness Level, Kinesiophobia, and Health-Related Quality of Life in Patients with Rheumatic and Musculoskeletal Diseases: A Network Analysis Introduction: Using a network analysis, the present study investigated the extent...
  11. Andy

    How to do things with words Two seminars on the naming of functional (psychogenic, non-epileptic, dissociative, conversion) seizures, 2021,Stone et al

    Highlights An interdisciplinary review of patients’ and professionals perceptions of the functions and effects of naming of psychogenic non-epileptic seizures. Presents a range of considerations for and against different choices of nomenclature. Arguments for, and a trajectory towards...
  12. Andy

    Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders, 2021, Eijsbout

    Abstract Irritable bowel syndrome (IBS) results from disordered brain–gut interactions. Identifying susceptibility genes could highlight the underlying pathophysiological mechanisms. We designed a digestive health questionnaire for UK Biobank and combined identified cases with IBS with...
  13. Andy

    Austria: Petition: ME / CFS: Recognition, Medical Care and Protection of the Affected, and Research Funding, closes 22 Nov 2021

    I'm relying on Google translation here, if any errors are spotted please let me know. Quote: Myalgic Encephalomyelitis / Chronic Fatigue Syndrome - ICD-10 G93.3 ME / CFS is a severe multi-system disease that currently affects between 26,000 and 80,000 people in Austria [1]. Depending on its...
  14. Sly Saint

    NHS England MUS page updated June 2021

    https://www.nhs.uk/conditions/medically-unexplained-symptoms/ should this page not now say " ME/CFS" and link to the new NICE guideline and specify that if diagnosed with ME/CFS (or ME/CFS is suspected) people should seek advice on ME/CFS 'treatment'.
  15. Dolphin

    Screening of a Small Number of Italian COVID-19 Syndrome Survivors by Means of the Fatigue Assessment Scale, 2021, Serafini

    https://www.mdpi.com/2673-8112/1/3/44 Screening of a Small Number of Italian COVID-19 Syndrome Survivors by Means of the Fatigue Assessment Scale: Long COVID Prevalence and the Role of Gender by Antonella Serafini 1,*, Alberto Tagliaferro 2,3,* Francesco Balbi 1, Alberto Bordo 1, Stefano...
  16. Dolphin

    Investigating the neural underpinnings of Chronic Fatigue: A multi-modal approach, 2021, Rayhan (PhD thesis)

    Source: Howard University Date: April 16, 2021 URL: https://www.proquest.com/openview/c0a823ec519e5e6acdd89c29ff4a4b2a/1 Investigating the neural underpinnings of Chronic Fatigue: A multi-modal approach ---------------------------------------------------------- Rakib U. Rayhan -...
  17. Andy

    Potential long COVID-19 gastrointestinal symptoms 6 months after coronavirus infection are associated with mental health symptoms, 2021,Blackett et al

    This survey study, nested within a prospective cohort of COVID-19 survivors with a minimum of 6 months of follow-up time, assessed the hypothesis that mental health symptoms both preceding and following COVID-19 infection would be associated with post-COVID chronic GI symptoms (see Methods...
  18. ahimsa

    USA: News from #MEAction

    This information is from the ME Action website, see http://www.meaction.net/2017/10/30/new-living-w-me-support-group-2/ The November and December schedule for the Living w/ ME Support Group has just been announced: Sunday, November 12: Avoiding Crashes Sunday, December 10: Surviving the...
  19. Mij

    Autoimmunity Increases Susceptibility to and Mortality from Sepsis, 2021, Jensen et al

    Abstract We recently demonstrated how sepsis influences the subsequent development of experimental autoimmune encephalomyelitis (EAE) presented a conceptual advance in understanding the postsepsis chronic immunoparalysis state. However, the reverse scenario (autoimmunity prior to sepsis) defines...
  20. SNT Gatchaman

    COVID-19 induces neuroinflammation and loss of hippocampal neurogenesis, Klein et al, 2021

    COVID-19 induces neuroinflammation and loss of hippocampal neurogenesis Robyn Klein, Allison Soung, Cheick Sissoko, Anna Nordvig, Peter Canoll, Madeline Mariani, Xiaoping Jiang, Traci Bricker, James Goldman, Gorazd Rosoklija, Victoria Arango, Mark Underwood, John Mann, Adrianus Boon, Andrew...
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