me/cfs

Video: Fatigue, Pacing and PEM Management | Lessons from ME/CFS - With Dr Ben Marsh I know this video has been mentioned on another thread but I think it might have been missed by many and deserves a thread of its own. In Episode 3 of our expert interviews series, Dr Asad Khan talks to Dr Ben...

There are some issues and concerns around the IDO2 tryptophan trap hypothesis about ME. These are my current thought directions, and should not be considered scientific fact. Please comment, add links, agree or disagree, or move this post to somewhere better if you are a moderator. Concerns...

Split from Effect of Galantamine Hydrobromide in Chronic Fatigue Syndrome A Randomized Controlled Trial, 2004, Blacker et al.. The quote in this post refers to the Blacker paper. This might also be of interest. It's the main result of an open-label study by Vermeulen et al. published in 2004...

(Note that this is an old study from 2004) Abstract Context: There is no established pharmacological treatment for the core symptoms of chronic fatigue syndrome (CFS). Galantamine hydrobromide, an acetyl cholesterone inhibitor, has pharmacological properties that might benefit patients with...

Funded study in progress. Abstract: Background: Paediatric Chronic Fatigue Syndrome or Myalgic Encaphalistis (CFS/ME) is disabling and relatively common (1-2% of teenagers). We need to improve treatment but need a well developed Patient Reported Outcome Measure (PROM) to do this. Clinical...

Abstract The Wessely School’s (WS) approach to medically unexplained symptoms, myalgic encephalomyelitis and chronic fatigue syndrome (MUS/MECFS) is critically reviewed using scientific criteria. Based on the ‘Biopsychosocial Model’, the WS proposes that patients’ dysfunctional beliefs...

A person-centred test of multidimensional perfectionism and health in people with chronic fatigue syndrome versus healthy controls Fuschia M. Sirois, Loren Toussaint, Jameson K. Hirsch, Niko Kohls, Martin Offenbacher Abstract: Theory and evidence suggests that person-centred models may be...

Abstract Background: Chronic fatigue syndrome (CFS) is a complex disease with few effective and safe therapies. Young Yum Pill (YYP), a proprietary herbal drug, has been used to relieve CFS-like symptoms. The pharmacological basis of this application of YYP is unknown. Purpose: This study...

Preprint Abstract A proportion of patients surviving acute COVID-19 infection develop post-COVID syndrome (long COVID) encompassing physical and neuropsychiatric symptoms lasting longer than 12 weeks. Here we studied a prospective cohort of individuals with long COVID (the ADAPT study) compared...

Trends in Molecular Medicine Insights from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome May Help Unravel the Pathogenesis of Post-Acute COVID-19 Syndrome Anthony L. Komaroff, W. Ian Lipkin Highlights • In some people, the aftermath of acute COVID-19 is a lingering illness with fatigue...

Abstract Post-exertional malaise (PEM), the key feature of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), is characterized by baseline symptom exacerbation after exposure to a stressor, and some patients can experience new or non-typical symptoms. We hypothesized that new or...

https://pubmed.ncbi.nlm.nih.gov/23580077/ I don't know what criteria they used but it seems interesting that such a high percentage tested positive for mould. Question is, is this a cause or an effect?

The paper comparing results in female CF And ME/CFS patients is posted later on the thread here and had its own thread that is now closed and the discussions merged Comparing Idiopathic Chronic Fatigue and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) in Males: Response to Two-Day...

"This publication is provided for historical reference only and the information may be out of date." Introduction The AHRQ evidence report on the Diagnosis and Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome was published in December, 2014 and provided a literature review for...

"David J Black explores the dangers of orthodoxy in the first in a four-part medico-legal series. “Orthodoxy” wrote Bertrand Russell “is the death of intelligence”. Before placing this in a medico-legal context with specific reference to the 2009 case Fraser and another v The National Institute...

Abstract In a previous study using mobile-health technology (mHealth), we reported a robust association between chronic fatigue symptoms and heart rate variability (HRV) in female patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). This study explores HRV analysis as an...

Abstract Post-exertional malaise (PEM) is regarded as the hallmark symptom in chronic fatigue syndrome (CFS). The aim of the current study is to explore differences in CFS patients with and without PEM in indicators of aortic stiffness, autonomic nervous system function, and severity of...

Abstract Coenzyme Q10 (CoQ10) is an essential cofactor in oxidative phosphorylation (OXPHOS), present in mitochondria and cell membranes in reduced and oxidized forms. Acting as an energy transfer molecule, it occurs in particularly high levels in the liver, heart, and kidneys. CoQ10 is also an...

Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex, multi-system disease whose etiological basis has not been established. Enteroviruses (EVs) as a cause of ME/CFS have sometimes been proposed, as they are known agents of acute respiratory and gastrointestinal...

J.L. Newton 1 J. Pairman 1 K. Hallsworth 1, 2 S. Moore 1,2 T. Plo TZ 3 and M.I. Trenell 1, 2 1. UK National Institute for Health Research Biomedical Research Centre in Ageing & Age-related Disease, Institute for Ageing and Health, Newcastle University, Newcastle, UK, 2. MRC Centre for Brain...