mitochondria

  1. Andy

    Mitochondrial complex III is essential for suppressive function of regulatory T cells, 2019, Chandel et al

    Open access (PDF file) at https://www.nature.com/articles/s41586-018-0846-z.epdf?shared_access_token=WAkCBVS3L3DO0bM6CbjKJ9RgN0jAjWel9jnR3ZoTv0NUSr5JeVHn5ILb4ngHL_BsTJMx2GJRjntjSBzshFZ8yE4tC3l6CzSLy6_zVux-gc6CNyCRZyfQaZAXy__EeJqkVjgWHo5q5hftEAvdjdhYIjKN3PqYRuicN1bmJ64vvgs%3D
  2. Andy

    Mitochondria Play an Unexpected Role in Killing Bacteria

    https://www.the-scientist.com/the-literature/mitochondria-play-an-unexpected-role-in-killing-bacteria-65246
    • Andy
    • Thread
    • immunology macrophages mitochondria mitochondrial function pathogens reactive oxygen species white blood cells
    • Replies: 6
    • Forum: Other health news and research
  3. Andy

    Chronic fatigue syndrome and mitochondrial dysfunction, 2009, Myhill et al

    An old study but, as shown in this thread, https://s4me.info/threads/top-10-sc...f-citations-tweet-by-dr-mark-gutheridge.7461/, one of the most cited ME/CFS papers in the past 10 years, so thought it might be useful to have here. Open access at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680051/
    • Andy
    • Thread
    • 2009 metabolism mitochondria myhill neutrophils oxidative phosphorylation
    • Replies: 1
    • Forum: ME/CFS research
  4. Andy

    A predictive algorithm to identify genes that discriminate individuals with fibromyalgia syndrome diagnosis from healthy controls, 2018, Saliqan et al

    Open access at https://www.dovepress.com/a-predictive-algorithm-to-identify-genes-that-discriminate-individuals-peer-reviewed-fulltext-article-JPR
  5. Andy

    SMCI RAMSAY 2018: “Biomarkers of mitochondrial dysfunction and signaling in ME/CFS”, Blomberg and Rosen

    2018 Ramsay Award recipients https://solvecfs.org/ramsay-2018-meet-professor-jonas-blomberg-md-phd-dr-anders-rosen-md-phd/
    • Andy
    • Thread
    • 2018 biomarker blomberg immunology me/cfs mitochondria paper rosen solve mecfs initiative
    • Replies: 2
    • Forum: ME/CFS research
  6. Andy

    Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2, 2018, Goffart et al

    Open access at https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gky793/5088042
  7. Andy

    Parkin and PINK1 mitigate STING-induced inflammation, 2018, Youle et al

    Paywalled at https://www.nature.com/articles/s41586-018-0448-9 Article from Nature about this study https://www.nature.com/articles/d41586-018-05988-z
  8. Indigophoton

    Metabolic features and regulation of the healing cycle—A new model for chronic disease pathogenesis and treatment, Robert K Naviaux, 2018

    Not specifically about ME, but includes CFS in the list of conditions considered. https://www.sciencedirect.com/science/article/pii/S1567724918301053#tf0005
    • Indigophoton
    • Thread
    • 2018 allostatic load antipurinergic therapy cell danger response chronic illness healing cycle integrated stress response m0 m1 m2 mitochondria metabokines metabolic memory mitochondria mitochondrial nexus naviaux purinergic signaling
    • Replies: 71
    • Forum: Other health news and research
  9. Inara

    Viruses Attack Mitochondria to Travel and Spread Within the Nervous System

    Didn't find it elsewhere: I've just realized the publication and article are from 2012: https://www.cell.com/cell-host-microbe/fulltext/S1931-3128%2812%2900104-7 (Kramer, Engquist). Maybe still interesting for "ME newbies" (like myself)? And what did become of it?
  10. Andy

    Nature: Newly made mitochondrial DNA drives inflammation

    https://www.nature.com/articles/d41586-018-05764-z
  11. A

    Mitochondrial research

    Thought this was interesting http://www.sciencemag.org/news/2016/02/why-do-our-cells-power-plants-have-their-own-dna
  12. Andy

    Diverse Roles of Mitochondria in Immune Responses: Novel Insights Into Immuno-Metabolism, 2018, Tan et al

    Open access at https://www.frontiersin.org/articles/10.3389/fimmu.2018.01605/full
  13. Andy

    Mitochondrial redox sensing by the kinase ATM maintains cellular antioxidant capacity, 2018, Zhang et al

    No idea if it's of interest to us but it sounds impressive. Paywalled at http://stke.sciencemag.org/content/11/538/eaaq0702.full
  14. Indigophoton

    Dying Organs Restored to Life in Novel Experiments

    Very interesting use of mitochondria - as transplants to replace damaged versions in human organs. https://mobile.nytimes.com/2018/07/10/health/mitochondria-transplant-heart-attack.html
  15. Indigophoton

    Reduced glycolytic reserve in isolated natural killer cells from ME/CFS patients: A preliminary investigation, Nguyen et al, 2018

    https://www.ncbi.nlm.nih.gov/pubmed/29981562 The DOI (digital object identifier, aka ID number) for this doesn't seem to work, so I'm not sure anything beyond the abstract has been published yet.
    • Indigophoton
    • Thread
    • 2018 glycolysis immunology marshall-gradisnik me/cfs mitochondria natural killer cells ncned nguyen paper staines
    • Replies: 22
    • Forum: ME/CFS research
  16. Andy

    Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress, 2018, Lee et al

    Paywalled at https://www.cell.com/cell-metabolism/abstract/S1550-4131(18)30390-5 Article on the study https://news.usc.edu/145046/mitochondrial-dna-nuclear-dna-work-together-usc-study/
  17. Sly Saint

    Disease-causing stomach bug attacks energy generation in host cells

    " Researchers report in a new study that the bacterium Helicobacter pylori - a major contributor to gastritis, ulcers and stomach cancer—resists the body's immune defenses by shutting down energy production within the cells of the stomach lining that serve as a barrier to infection. " The human...
  18. Indigophoton

    Impaired energy production may explain why brain is susceptible to age-related diseases

    This may be of interest to some, The article, https://medicalxpress.com/news/2018-05-impaired-energy-production-brain-susceptible.amp The paper, https://www.cell.com/cell-reports/fulltext/S2211-1247(18)30703-4
  19. Indigophoton

    Rehabilitating lactate: From poison to cure

    The article, https://phys.org/news/2018-05-lactate-poison.amp The paper, https://www.cell.com/cell-metabolism/fulltext/S1550-4131(18)30186-4? Full paper here, http://sci-hub.tw/10.1016/j.cmet.2018.03.008
  20. Indigophoton

    GABA, GABA, GABA, what does it actually do in the brain?

    This might be of background interest to some. https://medicalxpress.com/news/2018-05-gaba-brain.amp
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