Abstract Regulatory T cells (Treg cells), a distinct subset of CD4+ T cells, are necessary for the maintenance of immune self-tolerance and...
According to biology textbooks, a macrophage engulfs a bacterium, internalizes it in a toxin-filled vesicle called a phagosome, then shuttles the...
An old study but, as shown in this thread, https://s4me.info/threads/top-10-sc...f-citations-tweet-by-dr-mark-gutheridge.7461/, one of the most...
Objectives: Fibromyalgia syndrome (FMS) is a chronic and often debilitating condition that is characterized by persistent fatigue, pain, bowel...
2018 Ramsay Award recipients “Biomarkers of mitochondrial dysfunction and signaling in ME/CFS” A project summary as written by Profs. Blomberg...
Abstract Maintenance of topological homeostasis is vital for gene expression and genome replication in all organisms. Similar to other circular...
Abstract Although serum from patients with Parkinson’s disease contains elevated levels of numerous pro-inflammatory cytokines including IL-6,...
Not specifically about ME, but includes CFS in the list of conditions considered. Highlights for Mitochondrion •Four stages of the healing cycle...
Didn't find it elsewhere: Observed for the first time in neurons, biologists from Princeton University documented common strains of the herpes...
The innate immune response mounts a defence when immune cells recognize general hallmarks of infection, such as lipopolysaccharide (LPS)...
Thought this was interesting http://www.sciencemag.org/news/2016/02/why-do-our-cells-power-plants-have-their-own-dna
Lack of immune system cells or impairment in differentiation of immune cells is the basis for many chronic diseases. Metabolic changes could be...
No idea if it's of interest to us but it sounds impressive. Antioxidant role of ATM The kinase ATM is integral to repairing damaged DNA. Hence,...
Very interesting use of mitochondria - as transplants to replace damaged versions in human organs. An unusual transplant may revive tissues...
Abstract BACKGROUND: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is medically unexplained post-exertional fatigue associated with...
Highlights •MOTS-c, a peptide encoded by the mitochondrial DNA, can localize to the nucleus •Metabolic stress triggers AMPK-dependent...
" Researchers report in a new study that the bacterium Helicobacter pylori - a major contributor to gastritis, ulcers and stomach cancer—resists...
This may be of interest to some, [IMG] Aged mitochondria (green) in old neurons (gray) appear mostly as small punctate dots rather than a large...
George Brooks has been trying to reshape thinking about lactate—in the lab, the clinic and on the training field—for more than 40 years, and...
This might be of background interest to some. Gamma-Aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the brain. It is the...
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