mitochondria

  1. Andy

    Individual physiological and mitochondrial responses during 12 weeks of intensified exercise, 2021, Jacques et al

    Abstract Aim Observed effects of exercise are highly variable between individuals, and subject-by-training interaction (i.e., individual response variability) is often not estimated. Here, we measured mitochondrial (citrate synthetase, cytochrome-c oxidase, succinate dehydrogenase, and...
  2. InitialConditions

    Public ‘Social’ Mitochondria, Whispering Between Cells, Influence Health - Quanta Magazine

    https://www.quantamagazine.org/social-mitochondria-whispering-between-cells-influence-health-20210706 "Mitochondria appear to communicate and cooperate with one another, both within and between cells. Biologists are only just beginning to understand how and why."
  3. Kalliope

    biomolecules: Bioenergetic and Proteomic Profiling of Immune Cells in ME/CFS Patients: An Exploratory Study - Fernandez-Guerra et al - 2021

    biomolecules: Bioenergetic and Proteomic Profiling of Immune Cells in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients: An Exploratory Study Fernandes-Guerra et al Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a heterogeneous, debilitating, and complex...
    • Kalliope
    • Thread
    • 2021 acetyl co a atp coenzyme a denmark fernandez-guerra me/cfs metabolomics mitochondria mitochondrial dysfunction paper proteomics pyruvate dehydrogenase complex seahorse
    • Replies: 9
    • Forum: ME/CFS research
  4. A

    Scientific American: Could Mitochondria Be the Key to a Healthy Brain?, 2021, Kwon

    Interesting article - a lot if physiological/ psychiatric research but could be relevant subject for many other specialities. https://www.scientificamerican.com/article/could-mitochondria-be-the-key-to-a-healthy-brain/
  5. Sly Saint

    Tiny thermometer measures how mitochondria heat up the cell by unleashing proton energy: 2019

    https://www.sciencedaily.com/releases/2019/08/190829184202.htm
  6. Sly Saint

    Measuring mitochondrial function

    Copied post this might be of interest from 2007 Assay: Measurement of Mitochondrial Function https://www.genengnews.com/magazine/80/assay-measurement-of-mitochondrial-function/
  7. M

    The Pathogenesis of Long-Term Neuropsychiatric COVID-19 and the Role of Microglia, Mitochondria, and Persistent Neuroinflammation, 2021, Stefano et al

    Full title: Editorial: The Pathogenesis of Long-Term Neuropsychiatric COVID-19 and the Role of Microglia, Mitochondria, and Persistent Neuroinflammation: A Hypothesis (2021) Stefano et al. Abstract: Persistent comorbidities occur in patients who initially recover from acute coronavirus disease...
    • Milo
    • Thread
    • long covid microglia mitochondria neuroinflammation
    • Replies: 8
    • Forum: Long Covid research
  8. Andy

    Reduction of host cell mitochondrial activity as Mycobacterium leprae’s strategy to evade host innate immunity, 2021, Oliveira et al

    Abstract Leprosy is a much‐feared incapacitating infectious disease caused by Mycobacterium leprae or M lepromatosis, annually affecting roughly 200,000 people worldwide. During host‐pathogen interaction, M leprae subverts the immune response, leading to development of disease. Throughout the...
  9. Sly Saint

    Lymphoblastoid Cell Lines as Models to Study Mitochondrial Function in Neurological Disorders, 2021, Annesley and Fisher

    Abstract Neurological disorders, including neurodegenerative diseases, are collectively a major cause of death and disability worldwide. Whilst the underlying disease mechanisms remain elusive, altered mitochondrial function has been clearly implicated and is a key area of study in these...
    • Sly Saint
    • Thread
    • 2021 annesley biomarker fisher lcl lymphoblasts me/cfs mitochondria
    • Replies: 0
    • Forum: ME/CFS research
  10. Sly Saint

    Pathophysiology of skeletal muscle disturbances in (ME/CFS): 2021, Wirth, Scheibenbogen

    Abstract Chronic Fatigue Syndrome or Myalgic Encephaloymelitis (ME/CFS) is a frequent debilitating disease with an enigmatic etiology. The finding of autoantibodies against ß2-adrenergic receptors (ß2AdR) prompted us to hypothesize that ß2AdR dysfunction is of critical importance in the...
    • Sly Saint
    • Thread
    • energy germany me/cfs mitochondria muscle scheibenbogen vasodilation wirth
    • Replies: 14
    • Forum: ME/CFS research
  11. D

    Excessive exercise training causes mitochondrial functional impairment and decreases glucose tolerance in healthy volunteers, Flockhart et al, 2021

    https://doi.org/10.1016/j.cmet.2021.02.017 "Exercise training positively affects metabolic health through increased mitochondrial oxidative capacity and improved glucose regulation and is the first line of treatment in several metabolic diseases. However, the upper limit of the amount of...
  12. Andy

    USP30 protects against oxygen-glucose deprivation/reperfusion induced [mito] fragmentation & ubiquitination & degradation of MFN2, Chen et al, 2021

    Full title: USP30 protects against oxygen-glucose deprivation/reperfusion induced mitochondrial fragmentation and ubiquitination and degradation of MFN2 Open access, https://www.aging-us.com/article/202629/text
  13. John Mac

    Dysregulated Provision of Oxidisable Substrates to the Mitochondria in ME/CFS Lymphoblasts, 2021, Missailidis et al

    https://www.mdpi.com/1422-0067/22/4/2046
    • John Mac
    • Thread
    • amino acid catabolism beta-oxidation fisher glycolysis me/cfs missailidis mitochondria proteomics tca cycle transcriptomics
    • Replies: 68
    • Forum: ME/CFS research
  14. John Mac

    A systematic review of nutraceutical interventions for mitochondrial dysfunctions in ME/CFS, 2021, Marshall-Gradisnik et al

    https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-021-02742-4
    • John Mac
    • Thread
    • 2021 marshall-gradisnik mitochondria mitochondrial dysfunction nutraceutical review staines treatment
    • Replies: 3
    • Forum: ME/CFS research news
  15. Andy

    Mitochondrial morphodynamics alteration induced by influenza virus infection as a new antiviral strategy, Irene Pila-Castellanos et al, 2021

    Open access, https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1009340
  16. Sly Saint

    Host mitochondrial transcriptome response to SARS-CoV-2 in multiple cell models and clinical samples, Miller et al, 2021

    https://www.nature.com/articles/s41598-020-79552-z see also article about the research https://www.thailandmedical.news/news/covid-19-news-sars-cov-2-coronavirus-attacks-mitochondria,-the-power-house-of-cells-in-human-host-constant-fatigue-could-result-from-this
  17. leokitten

    The Artemisinin-Derived Autofluorescent Compound BG95 Exerts Strong Anticytomegaloviral Activity. Wild et al. Int J Mol Sci 2020

    Full title: The Artemisinin-Derived Autofluorescent Compound BG95 Exerts Strong Anticytomegaloviral Activity Based on a Mitochondrial Targeting Mechanism Another paper examining virus-induced mitochondrial fragmentation/fission in this case by HCMV and effects of an artesunate-derived...
    • leokitten
    • Thread
    • antiviral drugs artemisinin cytomegalovirus mitochondria mitochondrial architecture mitochondrial fragmentation mitochondrial function
    • Replies: 0
    • Forum: Other health news and research
  18. Sly Saint

    Age-related fatigue is associated with reduced mitochondrial function in peripheral blood mononuclear cells : Herpich et al 2020

    https://www.sciencedirect.com/science/article/abs/pii/S0531556520305258?dgcid=rss_sd_all
  19. Trish

    Role of mitochondria, oxidative stress and the response to antioxidants in ME/CFS: a possible approach to SARS-CoV-2 ‘long-haulers’?, 2020, Tate et al

    Review article: Role of mitochondria, oxidative stress and the response to antioxidants in myalgic encephalomyelitis/chronic fatigue syndrome: a possible approach to SARS-CoV-2 ‘long-haulers’? EmilyWood, Katherine H.Hall, WarrenTate (University of Otago, New Zealand)...
    • Trish
    • Thread
    • 2020 antioxidants coq10 katherine hall long covid me/cfs mitochondria mitoq oxidative stress warren tate
    • Replies: 1
    • Forum: Long Covid research
  20. Andy

    Mitochondria-derived methylmalonic acid, a surrogate biomarker of mitochondrial dysfunction and oxidative stress..., 2020, Wang et al

    Full title: Mitochondria-derived methylmalonic acid, a surrogate biomarker of mitochondrial dysfunction and oxidative stress, predicts all-cause and cardiovascular mortality in the general population Open access, https://www.sciencedirect.com/science/article/pii/S2213231720309460
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