Seen the following article recently shortly after a sibling participated in a similar study
https://mecfsskeptic.com/psychosomatic-history-of-multiple-sclerosis/
this too though much older - https://forum.mssociety.org.uk/t/mi...research-at-the-heart-of-disability-cuts/9260
shocking and a...
Hello everybody,
I have severe ME/CFS since 2016 and recently a multiple sclerosis (July 2022). I would like to point out that the previous MRIs were perfectly normal (between 2016 and 2022). Does anyone have both diseases?
I tag Jonathan Edwards (WE discussed by email in 2018)
Thanks, David
Mood Symptoms and Chronic Fatigue Syndrome due to Relapsing-Remitting Multiple Sclerosis Are Associated with Immune Activation and Aberrations in the Erythron
Abstract:
Background: Multiple sclerosis (MS) is a chronic autoimmune and neuroinflammatory disease of the central nervous system...
Developing, optimising and implementing a blended digital self-management tReatmEnt for FatigUe in multiplE scLerosis (REFUEL-MS)
https://fundingawards.nihr.ac.uk/award/NIHR203290
https://www.refuel-ms.com/
Chief Investigator(s):
Professor Rona Moss-Morris
Co-investigators
Start Date...
biopsychosocial model
cbt
cognitive behavioral model
digital therapeutics
fatigue
funding
get
kcl
london
moss-morris
multiplesclerosis
nihr
refuel-ms study
research
research methodology
uk clinics
Association Between Time Spent Outdoors and Risk of Multiple Sclerosis
Prince Sebastian; Nicolas Cherbuin; Lisa F. Barcellos; Shelly Roalstad; Charles Casper; Janace Hart; Gregory S. Aaen; Lauren Krupp; Leslie Benson; Mark Gorman; Meghan Candee; Tanuja Chitnis; Manu Goyal; Benjamin Greenberg...
Extensive Brain Pathologic Alterations Detected with 7.0-T MR Spectroscopic Imaging Associated with Disability in Multiple Sclerosis
Eva Heckova; Assunta Dal-Bianco; Bernhard Strasser; Gilbert J. Hangel; Alexandra Lipka; Stanislav Motyka; Lukas Hingerl; Paulus S. Rommer; Thomas Berger; Petra...
Post copied from the DecodeME thread:
I agree the 85% response rate is fantastic - unheard of really. Decode ME is such a brilliant study.
On a related note, I found the following UCSF and University of Cambridge study on MS, published yesterday, interesting:
Scientists identify first genetic...
Abstract
Introduction: Fatigue is the most common and disabling symptom in multiple sclerosis (MS), being reported by 55% to 78% of patients with multiple sclerosis (PwMS). Etiology of MS-related fatigue remains poorly understood but an increased neuromuscular fatigability (i.e., greater loss of...
Abstract
Multiple sclerosis (MS) and Myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) share the symptom of fatigue, and might even coexist together. Specifically focusing on genetics, pathophysiology, and neuroimaging data, we discuss an overview of the parallels, correlation, and...
Abstract
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system, for which and Epstein-Barr virus (EBV) infection is a likely prerequisite. Due to the homology between Epstein-Barr nuclear antigen 1 (EBNA1) and alpha-crystallin B (CRYAB), we examined antibody reactivity...
Cross-talk between brain cells and peripheral immune cells can modulate the progression of multiple sclerosis (MS), Mount Sinai researchers have discovered. Their findings reveal a previously unknown way in which the brain and immune system talk to each other and may identify a new therapeutic...
Abstract
While age-associated B cells (ABCs) are known to expand and persist following viral infection and during autoimmunity, their interactions are yet to be studied together in these contexts.
Here, we directly compared CD11c+T-bet+ ABCs using models of Epstein-Barr virus (EBV)...
Abstract
Multiple sclerosis (MS) is a T cell-driven autoimmune disease that attacks the myelin of the central nervous system (CNS) and currently has no cure. MS etiology is linked to both the gut flora and external environmental factors but this connection is not well understood. One immune...
Background: Individuals with multiple sclerosis (MS) are vulnerable to all types of infection, because MS itself involves immunodeficiency, in addition to involving treatment with immunosuppressants. Simple predictive variables for infection that are easily assessed in daily examinations are...
Do Human Endogenous Retroviruses Contribute to Multiple Sclerosis, and if So, How?
Morris G, Maes M, Murdjeva M, Puri BK
The gammaretroviral human endogenous retrovirus (HERV) families MRSV/HERV-W and HERV-H (including the closely related HERV-Fc1) are associated with an increased risk of...
Open Access
Published: 08 January 2023
Sequence similarity between SARS-CoV-2 nucleocapsid and multiple sclerosis-associated proteins provides insight into viral neuropathogenesis following infection
Camille M. Lake &
Joseph J. Breen
Scientific Reports volume 13, Article number: 389 (2023)...
Highlights
• Disability level (assessed by six-minute walk test) in people with multiple sclerosis was estimated using the data collected from wearable devices in free-living conditions.
• Fitbit minute-level step counts were analysed from which features were extracted.
• Elastic net, gradient...
Washington Post: Animalia
Why this mammal eats its own brain — and why it could matter for you
Dino Grandoni
“It’s a crazy animal,” said Dechmann, a behavioral ecologist at the Max Planck Institute of Animal Behavior in Germany. “We can learn a lot from the shrews.”
To prepare for the depths...
Abstract
Background
Recent empirical literature on autoimmune diseases has focused extensively on the implementation and evaluation of psychosocial interventions. Psychotherapy and counselling processes for multiple sclerosis (MS) have gained special attention given the cognitive and behavioral...
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