multiple sclerosis

  1. rvallee

    Effect of a Tailored Activity Pacing Intervention on Fatigue and Physical Activity Behaviours in Adults with MS, 2020

    Effect of a Tailored Activity Pacing Intervention on Fatigue and Physical Activity Behaviours in Adults with Multiple Sclerosis https://www.mdpi.com/1660-4601/18/1/17/htm Not very relevant to us but always interesting to see how similar studies are run in other diseases. I am not aware if PEM...
  2. Sly Saint

    Relationship between Fatigue and Physical Activity in a Polish Cohort of Multiple Sclerosis Patients : Rzepka et al 2020

    https://www.mdpi.com/1010-660X/56/12/726?type=check_update&version=2
  3. J

    Safety and efficacy of amantadine, modafinil, and methylphenidate for fatigue in multiple sclerosis..., 2020, Nourbakhsh et al

    Safety and efficacy of amantadine, modafinil, and methylphenidate for fatigue in multiple sclerosis: a randomised, placebo-controlled, crossover, double-blind trial https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(20)30354-9/fulltext
  4. J

    Gut microbiota–specific IgA+ B cells traffic to the CNS in active multiple sclerosis, 2020 Probstel et al.

    https://immunology.sciencemag.org/content/5/53/eabc7191
  5. J

    Bifrontal transcranial direct current stimulation modulates fatigue in multiple sclerosis: a randomized sham-controlled study, Chalah, 2020

    https://link.springer.com/article/10.1007/s00702-020-02166-2
  6. J

    The Role of Ketamine Infusion for Patients with MS-Related Fatigue

    https://www.neurologyadvisor.com/topics/multiple-sclerosis/the-role-of-ketamine-infusion-for-patients-with-ms-related-fatigue/ Primary outcome of the study was negative. Reference Fitzgerald KC, Morris B, Soroosh A, et al. Pilot randomized active-placebo-controlled trial of low-dose ketamine...
  7. Webdog

    Behavioral practices of patients with multiple sclerosis during Covid-19 pandemic, 2020, Alnajashi/Jabbad

    Full text: https://doi.org/10.1371/journal.pone.0241103241103 Study of 176 Multiple Sclerosis (MS) patients in Saudi Arabia. Spacing mine.
  8. Andy

    Immunometabolic profiling of T cells from .. relapsing-remitting [MS] .. impairment in glycolysis and mitochondrial respiration, 2017, Matarese et al

    Full title: Immunometabolic profiling of T cells from patients with relapsing-remitting multiple sclerosis reveals an impairment in glycolysis and mitochondrial respiration Open access, https://www.metabolismjournal.com/article/S0026-0495(17)30217-2/fulltext
  9. Andy

    The Role of Iron Metabolism in Fatigue, Depression, and Quality of Life in Multiple Sclerosis Patients, 2020, Knyszyńska et al

    Note: The term "chronic fatigue syndrome" is used often in this paper. As far as I can see the authors actually mean "chronic fatigue", which is why I have opened this thread in the "Health News and Research unrelated to ME/CFS" sub-forum, not elsewhere. Open access...
  10. J

    Regional microglial activation in the substantia nigra is linked with fatigue in MS, 2020, Singhal et al.

    https://nn.neurology.org/content/7/5/e854 Popular article here Hunting for a "Hidden Pathology": Why Is Fatigue So Debilitating in Multiple Sclerosis? https://www.technologynetworks.com/neuroscience/news/hunting-for-a-hidden-pathology-why-is-fatigue-so-debilitating-in-multiple-sclerosis-339120
  11. Sly Saint

    Fatigue in Multiple Sclerosis Is Associated With Childhood Adversities: Pust et al Aug 2020

    https://www.frontiersin.org/articles/10.3389/fpsyt.2020.00811/full
  12. Andy

    A Comparison of Neuroimaging Abnormalities in Multiple Sclerosis, Major Depression and Chronic Fatigue Syndrome.., 2017, Morris et al

    Full title: A Comparison of Neuroimaging Abnormalities in Multiple Sclerosis, Major Depression and Chronic Fatigue Syndrome (Myalgic Encephalomyelitis): is There a Common Cause? Open access, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842501/
  13. J

    New MS Drug Approved — Ofatumumab is first self-administered, targeted B-cell treatment for relapsing MS

    Another drug for MS, still nothing for MECFS. https://www.medpagetoday.com/neurology/multiplesclerosis/88195
  14. J

    No Benefit of 3 Commonly Used Medications in MS Fatigue

    https://www.medscape.com/viewarticle/931397 might be paywalled
  15. J

    Pilot randomized active-placebo-controlled trial of low-dose ketamine for the treatment of multiple sclerosis–related fatigue, 2020, Fitzgerald et al

    Popular article https://multiplesclerosisnewstoday.com/news-posts/2020/07/07/pilot-randomized-active-placebo-controlled-trial-of-low-dose-ketamine-for-the-treatment-of-multiple-sclerosisrelated-fatigue/ Journal https://journals.sagepub.com/doi/abs/10.1177/1352458520936226?journalCode=msja
  16. Dolphin

    'Holy Grail' discovery could mean 'nobody needs to worry about their MS getting worse' – study

    Continues at: https://www.irishexaminer.com/world/arid-40027451.html Early days yet of course.
  17. Anna H

    Immuno-metabolic impact of the multiple sclerosis patients’ sera on endothelial cells of the blood-brain barrier (2020) Sheikh et al

    https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-020-01810-8 https://multiplesclerosisnewstoday.com/blood-factors-impair-metabolism-blood-brain-barrier-ms-study/ I thought this could be of interest, since one of Jarred Younger's upcoming studies is testing the hypothesis...
  18. Sly Saint

    Microbiome in Multiple Sclerosis; Where Are We, What We Know and Do Not Know : Boziki et al Apr 2020

    full paper: https://www.mdpi.com/2076-3425/10/4/234/htm
  19. Andy

    Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammation, 2020, Bhargarva et al

    Open access, https://www.jci.org/articles/view/129401
  20. Mij

    Autonomic nervous system: a key player in prodromal multiple sclerosis?

    https://link.springer.com/article/10.1007/s10286-020-00676-3 Autonomic dysfunction, namely gastrointestinal, genitourinary, and cardiovascular abnormalities, is a key feature of the prodromal phase of other neurological disorders, such as Parkinson disease and other synucleinopathies [6]...
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