multiple sclerosis

https://immunology.sciencemag.org/content/5/53/eabc7191

https://link.springer.com/article/10.1007/s00702-020-02166-2

https://www.neurologyadvisor.com/topics/multiple-sclerosis/the-role-of-ketamine-infusion-for-patients-with-ms-related-fatigue/ Primary outcome of the study was negative. Reference Fitzgerald KC, Morris B, Soroosh A, et al. Pilot randomized active-placebo-controlled trial of low-dose ketamine...

Full text: https://doi.org/10.1371/journal.pone.0241103241103 Study of 176 Multiple Sclerosis (MS) patients in Saudi Arabia. Spacing mine.

Full title: Immunometabolic profiling of T cells from patients with relapsing-remitting multiple sclerosis reveals an impairment in glycolysis and mitochondrial respiration Open access, https://www.metabolismjournal.com/article/S0026-0495(17)30217-2/fulltext

Note: The term "chronic fatigue syndrome" is used often in this paper. As far as I can see the authors actually mean "chronic fatigue", which is why I have opened this thread in the "Health News and Research unrelated to ME/CFS" sub-forum, not elsewhere. Open access...

https://nn.neurology.org/content/7/5/e854 Popular article here Hunting for a "Hidden Pathology": Why Is Fatigue So Debilitating in Multiple Sclerosis? https://www.technologynetworks.com/neuroscience/news/hunting-for-a-hidden-pathology-why-is-fatigue-so-debilitating-in-multiple-sclerosis-339120

https://www.frontiersin.org/articles/10.3389/fpsyt.2020.00811/full

Full title: A Comparison of Neuroimaging Abnormalities in Multiple Sclerosis, Major Depression and Chronic Fatigue Syndrome (Myalgic Encephalomyelitis): is There a Common Cause? Open access, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842501/

Another drug for MS, still nothing for MECFS. https://www.medpagetoday.com/neurology/multiplesclerosis/88195

https://www.medscape.com/viewarticle/931397 might be paywalled

Popular article https://multiplesclerosisnewstoday.com/news-posts/2020/07/07/pilot-randomized-active-placebo-controlled-trial-of-low-dose-ketamine-for-the-treatment-of-multiple-sclerosisrelated-fatigue/ Journal https://journals.sagepub.com/doi/abs/10.1177/1352458520936226?journalCode=msja

Continues at: https://www.irishexaminer.com/world/arid-40027451.html Early days yet of course.

https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-020-01810-8 https://multiplesclerosisnewstoday.com/blood-factors-impair-metabolism-blood-brain-barrier-ms-study/ I thought this could be of interest, since one of Jarred Younger's upcoming studies is testing the hypothesis...

full paper: https://www.mdpi.com/2076-3425/10/4/234/htm

Open access, https://www.jci.org/articles/view/129401

https://link.springer.com/article/10.1007/s10286-020-00676-3 Autonomic dysfunction, namely gastrointestinal, genitourinary, and cardiovascular abnormalities, is a key feature of the prodromal phase of other neurological disorders, such as Parkinson disease and other synucleinopathies [6]...

How and for whom does supportive adjustment to multiple sclerosis cognitive-behavioural therapy work? A mediated moderation analysis KimberleyGoldsmitha1Joanna L.Hudsonb1TrudieChaldercLauraDennisondRona MossMorrisb https://www.sciencedirect.com/science/article/abs/pii/S0005796720300450...

I thought this piece of (oldish) research might be of interest to people interested in measuring cognitive dysfunction in ME. It notes that self reported fatigue in MS doesn't correlate well with actual cognitive performance measures (which is the same in ME). Here, they developed a new...

What does MS fatigue feel like? (Aug 2, 2019) by Jennifer Huizen - Medical News Today I don't believe ME/CFS and MS are experiencing fatigue the same way, but I think it is interesting that MS, known to be a neurological disease, can have a profound type of fatigue they believe stems from the...