https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-022-03289-8
Benjamin H. Natelson
Jin-Mann S. Lin
Michelle Blate
Sarah Khan
Yang Chen
Elizabeth R. Unger
Open access
Background
Orthostatic intolerance-OI is common in Myalgic Encephalomyelitis/Chronic Fatigue...
Abstract
Purpose
Previous studies demonstrated M2 muscarinic acetylcholine receptor-activating autoantibodies (M2R-AAb) were present in some patients with postural tachycardia syndrome (POTS). This study examines how these autoantibodies might contribute to the pathophysiology of POTS, and...
Gluten-free diet in postural orthostatic tachycardia syndrome (POTS), 2022, Zha et al
Abstract
Objectives
Postural orthostatic tachycardia syndrome (POTS) is a chronic disorder of the autonomic nervous system that is associated with orthostatic intolerance (OI) and gastrointestinal (GI)...
Abstract
Background and objectives: Orthostatic intolerance (OI) is a clinical condition in which symptoms worsen upon assuming and maintaining upright posture and are ameliorated by recumbency. OI has a high prevalence in patients with myalgic encephalomyelitis/chronic fatigue syndrome...
Compression Stockings Improve Cardiac Output and Cerebral Blood Flow during Tilt Testing in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Patients: A Randomized Crossover Trial
Abstract
Background and Objectives: Orthostatic intolerance (OI) is a clinical condition in which...
Orthostatic Symptoms and Reductions in Cerebral Blood Flow in Long-Haul COVID-19 Patients: Similarities with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Abstract
Background and Objectives: Symptoms and hemodynamic findings during orthostatic stress have been reported in both long-haul...
Highlights
Long COVID symptoms include fatigue, brain fog, anosmia, dysgeusia, orthostatic intolerance
Long COVId symptoms overlap with those of chronic fatigue syndrome (ME/CFS) and POTS.
Reduced cerebral blood flow is a feature of dysautonomia in ME/CFS and POTS.
Stellate ganglion block...
Orthostatic intolerance syndromes after hematopoietic cell transplantation: clinical characteristics and therapeutic interventions in a single-center experience
Abstract
Background
Hematopoietic cell transplantation (HCT) is an established and potentially curative therapeutic option for...
Background and Objective: Migraineurs often complain of orthostatic intolerance (OI), and its recognition is vital to appropriate treatment. This study attempts to identify and characterize autonomic dysfunction, comparing a sample of migraineurs with OI with a sample of migraineurs without...
Abstract
Salt supplementation is a common non-pharmacological approach to the management of recurrent orthostatic syncope or presyncope, particularly for patients with vasovagal syncope (VVS) or postural orthostatic tachycardia syndrome (POTS), although there is limited consensus on the optimal...
In conclusion, meals do matter in the evaluation and treatment of POTS. There are significant postprandial symptoms in POTS patients, which are related to exaggerated postprandial tachycardia. Possible mechanisms include enhanced splanchnic blood pooling, an increased secretion of vasoactive...
Dr Jenny Butler, Consultant Physician - General Medicine, at Christchurch Hospital, is joining us online on Wed, 10th Nov 1.30pm to talk about Orthostatic Intolerance.
Many people with ME/CFS (Myalgic Encephalomyelitis /Chronic Fatigue Syndrome) experience triggering or worsening of symptoms...
Abstract
Background: Postural tachycardia syndrome (POTS) is a form of autonomic dysregulation and is characterized by an excessive heart rate (HR) increment upon the upright body position while blood pressure is maintained. Patients experience typical symptoms of orthostatic intolerance such as...
New paper on Salt: The paradoxical philosopher's stone of autonomic medicine - to expand intravascular volume or to raise blood pressure.
Highlights
Salt has profoundly shaped human history, including diet and medicine.
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Salt improves orthostatic tolerance but also increases risk of...
Mod note: A number of posts have been moved from a useful study on this subject:
Compression Garment Reduces Orthostatic Tachycardia and Symptoms in Patients With [POTS], 2021, Bourne et al
This is very interesting. I use compression wear, and swear it helps keep me functioning longer...
Compression Garment Reduces Orthostatic Tachycardia and Symptoms in Patients With Postural Orthostatic Tachycardia Syndrome
Kate M. Bourne et al
"Abstract
Background
Postural orthostatic tachycardia syndrome (POTS) is a chronic form of orthostatic intolerance associated with a significant...
https://pubmed.ncbi.nlm.nih.gov/34484936/
Abstract
Objective: Postural tachycardia syndrome (POTS), the most common form of dysautonomia, may be associated with autoimmunity in some cases. Autoantibodies against the ganglionic acetylcholine receptor (gAChR) have been reported in a minority of...
Post-Covid-19 Tachycardia Syndrome: A distinct phenotype of Post-acute Covid-19 Syndrome
Ståhlberg, Fedorowski et al
Abstract
In this paper we highlight the presence of tachycardia in Post-acute Covid-19 Syndrome by introducing a new label for this phenomenon: Post-covid-19 tachycardia...
Abstract
Key points
The impact of SARS-CoV-2 infection on autonomic and cardiovascular function in otherwise healthy individuals is unknown.
We show for the first time that young adults recovering from SARS-CoV-2 have elevated resting sympathetic activity, but similar heart rate and blood...
Abstract
The autonomic nervous system (ANS) can be affected by COVID-19, and dysautonomia may be a possible complication in post-COVID individuals. Orthostatic hypotension (OH) and postural tachycardia syndrome (POTS) have been suggested to be common after SARS-CoV-2 infection, but other...
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