orthostatic intolerance

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    Recording of online talk and Q&A: "Diagnosis and Management of Orthostatic Intolerance in ME/CFS" with Frans Visser MD PhD and Linda van Campen MD

    The YouTube link below relates to the April 8 online talk and Q&A with Professor Frans Visser and Dr Linda van Campen who are both Dutch experts/cardiologists/clinicians/researchers. This talk and Q&A session was arranged by the Irish ME Trust and the Irish ME/CFS Association. Q&A was edited...
  2. Mij

    The effect of water temperature on orthostatic tolerance: a randomised crossover trial, 2022, Lain T Parsons et al

    Abstract Purpose Bolus water drinking, at room temperature, has been shown to improve orthostatic tolerance (OT), probably via sympathetic activation; however, it is not clear whether the temperature of the water bolus modifies the effect on OT or the cardiovascular responses to orthostatic...
  3. Mij

    Salt

    Salt from the autonomic perspective, 2022, William P Cheshire - editorial https://www.sciencedirect.com/science/article/pii/S1566070222000297?dgcid=author#bb0005
  4. Mij

    Prospective Evaluation of Autonomic Dysfunction in Post-Acute Sequela of COVID-19, 2022, Sameer M Jamal et al

    Abstract Background: Patients with PASC often report symptoms of orthostatic intolerance and autonomic dysfunction. Numerous case reports link Postural Orthostatic Tachycardia Syndrome (POTS) to PASC. No prospective analysis has been performed. Objective: We performed head-up tilt table (HUTT)...
  5. Mij

    Effect of Upright Posture on Endothelial Function in Women and Men, 2022, Karim Habib et al

    Women are more prone to orthostatic intolerance compared to men and have a greater vasodilatory capacity. We investigated the hypothesis that women would have greater peripheral flow-mediated dilation (FMD) while in the upright posture compared to men, which could contribute to this phenomenon...
  6. Hutan

    Physiological assessment of orthostatic intolerance in chronic fatigue syndrome, 2022, Natelson et al

    https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-022-03289-8 Benjamin H. Natelson Jin-Mann S. Lin Michelle Blate Sarah Khan Yang Chen Elizabeth R. Unger Open access Background Orthostatic intolerance-OI is common in Myalgic Encephalomyelitis/Chronic Fatigue...
  7. Andy

    Transcutaneous vagus nerve stimulation attenuates autoantibody-mediated cardiovagal dysfunction & inflammation in a rabbit model of [POTS], 2022, Deng

    Abstract Purpose Previous studies demonstrated M2 muscarinic acetylcholine receptor-activating autoantibodies (M2R-AAb) were present in some patients with postural tachycardia syndrome (POTS). This study examines how these autoantibodies might contribute to the pathophysiology of POTS, and...
  8. Andy

    Gluten-free diet

    Gluten-free diet in postural orthostatic tachycardia syndrome (POTS), 2022, Zha et al Abstract Objectives Postural orthostatic tachycardia syndrome (POTS) is a chronic disorder of the autonomic nervous system that is associated with orthostatic intolerance (OI) and gastrointestinal (GI)...
  9. Sly Saint

    Psychogenic Pseudosyncope: Real or Imaginary? Results from a Case-Control Study in (ME/CFS) Patients, 2022, Visser

    Abstract Background and objectives: Orthostatic intolerance (OI) is a clinical condition in which symptoms worsen upon assuming and maintaining upright posture and are ameliorated by recumbency. OI has a high prevalence in patients with myalgic encephalomyelitis/chronic fatigue syndrome...
  10. Sly Saint

    Compression Stockings Improve Cardiac Output and Cerebral Blood Flow during Tilt Testing in (ME/CFS)Patients: A Randomized Crossover Trial, 2021,Rowe

    Compression Stockings Improve Cardiac Output and Cerebral Blood Flow during Tilt Testing in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Patients: A Randomized Crossover Trial Abstract Background and Objectives: Orthostatic intolerance (OI) is a clinical condition in which...
  11. Sly Saint

    Orthostatic Symptoms and Reductions in Cerebral Blood Flow in Long-Haul COVID-19 Patients: Similarities with ME/CFS, 2021, Rowe et al

    Orthostatic Symptoms and Reductions in Cerebral Blood Flow in Long-Haul COVID-19 Patients: Similarities with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Abstract Background and Objectives: Symptoms and hemodynamic findings during orthostatic stress have been reported in both long-haul...
  12. M

    Stellate ganglion block reduces symptoms of Long COVID: A case series (2021) Liu et al

    Highlights Long COVID symptoms include fatigue, brain fog, anosmia, dysgeusia, orthostatic intolerance Long COVId symptoms overlap with those of chronic fatigue syndrome (ME/CFS) and POTS. Reduced cerebral blood flow is a feature of dysautonomia in ME/CFS and POTS. Stellate ganglion block...
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    Orthostatic intolerance syndromes after hematopoietic cell transplantation, 2021, Vecchié et al

    Orthostatic intolerance syndromes after hematopoietic cell transplantation: clinical characteristics and therapeutic interventions in a single-center experience Abstract Background Hematopoietic cell transplantation (HCT) is an established and potentially curative therapeutic option for...
  14. Mij

    Autonomic Dysfunction among Migraineurs with and without Complaints of Orthostatic Intolerance: Evidence for Small Fiber Nerve Damage, 2021, Stillman

    Background and Objective: Migraineurs often complain of orthostatic intolerance (OI), and its recognition is vital to appropriate treatment. This study attempts to identify and characterize autonomic dysfunction, comparing a sample of migraineurs with OI with a sample of migraineurs without...
  15. Mij

    Salt supplementation in the management of orthostatic intolerance: Vasovagal syncope and postural orthostatic tachycardia syndrome, 2021 E.L Williams

    Abstract Salt supplementation is a common non-pharmacological approach to the management of recurrent orthostatic syncope or presyncope, particularly for patients with vasovagal syncope (VVS) or postural orthostatic tachycardia syndrome (POTS), although there is limited consensus on the optimal...
  16. Mij

    Do meals affect heart rate and symptoms inpostural orthostatic tachycardia syndrome? 2021, Kate M Bourne et al

    In conclusion, meals do matter in the evaluation and treatment of POTS. There are significant postprandial symptoms in POTS patients, which are related to exaggerated postprandial tachycardia. Possible mechanisms include enhanced splanchnic blood pooling, an increased secretion of vasoactive...
  17. Sly Saint

    Webinar: Orthostatic Intolerance /Dysautonomia: the types, the tests and the treatment /lifestyle management protocols, Nov 10th 2021

    Dr Jenny Butler, Consultant Physician - General Medicine, at Christchurch Hospital, is joining us online on Wed, 10th Nov 1.30pm to talk about Orthostatic Intolerance. Many people with ME/CFS (Myalgic Encephalomyelitis /Chronic Fatigue Syndrome) experience triggering or worsening of symptoms...
  18. Mij

    Orthostatic Cognitive Dysfunction in Postural Tachycardia Syndrome After Rapid Water Drinking, 2019, Belén Rodriguez et al

    Abstract Background: Postural tachycardia syndrome (POTS) is a form of autonomic dysregulation and is characterized by an excessive heart rate (HR) increment upon the upright body position while blood pressure is maintained. Patients experience typical symptoms of orthostatic intolerance such as...
  19. Mij

    Salt: The paradoxical philosopher's stone of autonomic medicine

    New paper on Salt: The paradoxical philosopher's stone of autonomic medicine - to expand intravascular volume or to raise blood pressure. Highlights Salt has profoundly shaped human history, including diet and medicine. • Salt improves orthostatic tolerance but also increases risk of...
  20. Keela Too

    Compression Garments

    Mod note: A number of posts have been moved from a useful study on this subject: Compression Garment Reduces Orthostatic Tachycardia and Symptoms in Patients With [POTS], 2021, Bourne et al This is very interesting. I use compression wear, and swear it helps keep me functioning longer...
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