This preprint is under consideration at Journal of Translational Medicine. Preprints are preliminary reports that have not undergone peer review. They should not be considered conclusive, used to inform clinical practice, or referenced by the media as validated information...
https://www.sciencedirect.com/science/article/abs/pii/S0828282X19315508
Edited to add: Full article https://www.onlinecjc.ca/article/S0828-282X(19)31550-8/fulltext
Canadian Journal of Cardiology
Volume 36, Issue 3, March 2020, Pages 357-372
Full title:
Cerebral blood flow is reduced in ME/CFS during head-up tilt testing even in the absence of hypotension or tachycardia: a quantitative, controlled study using Doppler echography
https://www.sciencedirect.com/science/article/pii/S2467981X20300044
Patients were classified as...
Moderator note: This post has been copied and following posts moved from this thread: Concerns about craniocervical instability surgery in ME/CFS
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Not really clear on how credible this statement is, at least in terms of POTS. I thought there were tachacardia and...
Currently crashing so this will be a bit short. Was 2 hrs out to meet doctors and by the end i struggled to walk and almost had a nervous breakdown (luckily i had so many panic attacks last year after worsening that i can feel incredibly terrible without freaking out about it) It got me...
The Benefits of Oral Rehydration on Orthostatic Intolerance in Children with Postural Tachycardia Syndrome
Marvin S. Medow, PhD, Kenneth Guber, BSm Shilpan Chokshi, BS, Courtney Terilli, BSN, Paul Visintainer, PhD, Julian M. Stewart, MD, PhD...
Recently, I walked for longer than usual. While I was still out of the house, I gradually became more symptomatic: weaker, fatigued, dizzy, etc. After eating a slice of pizza, these symptoms improved significantly despite still being on my feet and walking. I think that is an important...
Paradigme shift to disequilibrium in the genesis of orthostatic intolerance in patients with chronic fatigue syndrome
K Miwa
European Heart Journal, Volume 40, Issue Supplement_1, October 2019
https://doi.org/10.1093/eurheartj/ehz746.0311
https://www.physiology.org/doi/abs/10.1152/ajpheart.00680.2018?journalCode=ajpheart
This isn't ME/CFS research but it's not unrelated either, so I thought this should be in the ME/CFS research section.
I’ve previously considered myself to be unlikely to have POTS. I can be almost normally active on very good days (paid for later).
But a recent experience of tachycardia (110-135bpm when normal resting was 58-70) for days on end, and repeated instances in the days before and after that of...
I thought I'd put this in 'News' rather than 'Research' as it looks a bit amateurish. (Maybe Julia Newton was in a teaching capacity?) (He repeatedly misspells 'encephalomyelitis'.)
Source: International Journal of Therapy and Rehabilitation
Vol 26, #5
Date: June 6, 2019
URL...
Hi,
My question is has anybody tried fludrocortisone and has it made any difference?
My M. E. is very severe I am bedbound does anybody know whether this would assist in enabling me to sit up in bed?
I realise that you have to increase salt intake and wear compression stockings but I just...
This discussion has been split from the 2019 NIH conference thread
I don't understand that. Orthostatic intolerance is the inability to tolerate standing up. By definition you know you have that if you have it.
Maybe Dr Bateman is referring to haemodynamic changes that might be thought to...
https://doi.org/10.1371/journal.pone.0204419
My take away from this: patients with hypocapnic cerebral hypoperfusion present the same symptoms as patients with POTS but can fail a tilt test due to absence of tachycardia.
ME/CFS is also mentioned.
Full paper (PDF file), https://link.springer.com/epdf/10.1007/s10286-018-00586-5?shared_access_token=STPXS4PtJZOInVSXh8x-Mfe4RwlQNchNByi7wbcMAY660rig95e8st82z-CMxT4KiCk81BpD7DOoNq3KMVlYwM6FCVf_FXKtfFM1z-YvJJbjMgP9QCLqADOEFlJpB88Elu-TN36S3zHCJJbtNRbx7FEiObmkUmlXDKOql6z1yPE%3D
also paywalled at...
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