rct

  1. Ryan31337

    Randomized Trial of Ivabradine in Patients With Hyperadrenergic [POTS], 2021, Taub et al

    Paywall, https://www.jacc.org/doi/full/10.1016/j.jacc.2020.12.029 Now free access (Oct 2025)
  2. leokitten

    Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19 A Randomized Clinical Trial. Lenze et al. JAMA (2020)

    An SSRI to treat early COVID, supposedly SSRIs can inhibit SARS-CoV-2 and also potentially have anti-inflammatory and immunoregulatory properties. I think also earlier this year there was an observational study showing patients taking SSRIs had lower risk of severe COVID and death (I think a...
  3. MSEsperanza

    The difficulties of conducting intervention trials for the treatment of [ME/CFS]: Expert testimony to NICE guidelines committee by Jonathan Edwards

    Thought it could be helpful to have a thread on Jonathan's expert testimony for any further use and citation. Edwards, Jonathan CW (2020), The difficulties of conducting intervention trials for the treatment of myalgic encephalomyelitis/chronic fatigue syndrome: Expert testimony presented to...
  4. Sly Saint

    Acceptability and Effectiveness of NHS-Recommended e-Therapies for Depression, Anxiety, and Stress: Meta-Analysis: Simmonds-Buckley 2020

    https://www.jmir.org/2020/10/e17049/
  5. ME/CFS Science Blog

    Why do doctors use treatments that do not work? Doust & Del Mar, 2005

    Thought this was an interesting editorial. It's from 2004 but is still relevant. Source: http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC351829&blobtype=pdf
  6. ME/CFS Science Blog

    What’s in the pipeline? Ongoing, registered, or planned clinical trials for ME/CFS

    Evelien and I were interested in what clinical trials are currently planned or ongoing for ME/CFS. It can take many years to conduct a clinical trial and report the results, so we wanted to know what we can expect to come out in the next years. A search of databases that register clinical...
  7. Andy

    Effects of the prolong life with nine turn method (Yan Nian Jiu Zhuan) Qigong on patients with chronic fatigue syndrome, 2018, Xie et al

    Full title: Effects of the prolong life with nine turn method (Yan Nian Jiu Zhuan) Qigong on patients with chronic fatigue syndrome: study protocol for a randomized controlled trial Open access PDF available from http://apm.amegroups.com/article/view/48615
  8. Andy

    Recruiting Adolescents With [CFS/ME] to Internet-Delivered Therapy: Internal Pilot Within a Randomized Controlled Trial, 2020, Knoop, Crawley et al

    Full title: Recruiting Adolescents With Chronic Fatigue Syndrome/Myalgic Encephalomyelitis to Internet-Delivered Therapy: Internal Pilot Within a Randomized Controlled Trial Open access, https://www.jmir.org/2020/8/e17768/
  9. Grigor

    Protocol ReCOVer: A RCT testing the efficacy of CBT for preventing chronic post-infectious fatigue among patients diagnosed with COVID-19.

    Very troubling study by prof Knoop et al. "ONDERZOEKSVRAAG To investigate whether delivering timely Cognitive Behavioural Therapy [CBT], an evidence-based treatment for chronic fatigue, is effective in preventing the development of post-COVID-19 chronic fatigue. URGENTIE A substantial...
  10. Sly Saint

    Effectiveness of Psychological Interventions to Improve Quality of Life in People With Long-Term Conditions: Rapid Systematic Review of RCTs - 2018

    Effectiveness of Psychological Interventions to Improve Quality of Life in People With Long-Term Conditions: Rapid Systematic Review of Randomised Controlled Trials Niall Anderson 1 2 , Gozde Ozakinci 3 https://pubmed.ncbi.nlm.nih.gov/29587884/ eta: posted this study as is basis of...
  11. Sly Saint

    Cognitive behavioural therapy for adults with dissociative seizures (CODES): a ... multicentre, randomised controlled trial (2020) Goldstein, Chalder

    CODEs study group ProfLaura HGoldsteinPhDaEmily JRobinsonMScbgJohn D CMellersMRCPsychhProfJonStonePhDiProfAlanCarsonMDiProfMarkusReuberPhDjNickMedfordPhDhProfPaulMcCronePhDcJoannaMurrayBAdProfMark...
  12. Sly Saint

    The feasibility and acceptability of an early intervention in primary care to prevent CFS in adults: randomised controlled-O'Dowd, Crawley 2020

    The feasibility and acceptability of an early intervention in primary care to prevent chronic fatigue syndrome (CFS) in adults: randomised controlled trial https://pilotfeasibilitystudies.biomedcentral.com/articles/10.1186/s40814-020-00595-0
  13. cassava7

    OMF to launch clinical trials on Mestinon & Kynurenine, post-COVID19 study

    From their May Momentum 2020 newsletter & https://www.omf.ngo/maymomentum/ Post-COVID19 study: https://www.omf.ngo/2020/04/26/tracking-covid-19-patients/ Mestinon trial: https://www.omf.ngo/2020/04/26/the-mestinon-clinical-trial-for-me-cfs/ &...
    • cassava7
    • Thread
    • clinical trial covid-19 kynurenine me/cfs mestinon omf post covid-19 syndrome rct
    • Replies: 36
    • Forum: ME/CFS research news
  14. Dolphin

    A qualitative exploration of treatment preference in paediatric randomised controlled trials, 2019, Beasant (Crawley supervised)

    via Dr. Marc-Alexander Fluks Source: University of Bristol Date: November 28, 2019 URL: https://research-information.bris.ac.uk/en/theses/a-qualitative-exploration-of-treatment-preference-in-paediatric-randomised-controlled-trials(e6ff1d3b-e315-45e2-a4da-18ae0b414a1d).html...
  15. Andy

    Achieving symptom relief in patients with ME by targeting the neuro-immune interface and inducing disease tolerance (2020) Rodriguez et al

    Pre-print, https://www.biorxiv.org/content/10.1101/2020.02.20.958249v1 April 2023 - now published, see here Achieving symptom relief in patients with ME by targeting the neuro-immune interface and inducing disease tolerance (2020) Rodriguez et al ETA: Added word, "Pre-print".
    • Andy
    • Thread
    • 2020 inmest me/cfs paper rct rodriguez treatment vagus nerve
    • Replies: 41
    • Forum: ME/CFS research
  16. Dolphin

    Medicinal Herbs for Managing Fatigue Symptoms in Patients with Idiopathic Chronic Fatigue, 2020, Kim

    Looks like CFS may have been looked at in this. https://www.sciencedirect.com/science/article/abs/pii/S1876382019314076 View full text © 2020 Published by Elsevier GmbH.
    • Dolphin
    • Thread
    • 2020 chronic fatigue herbal medicine kim me/cfs paper rct review treatment
    • Replies: 8
    • Forum: ME/CFS research
  17. Hutan

    A randomised, placebo-controlled, double-blinded trial of duloxetine in the treatment of general fatigue in CFS, 2014, Arnold et al. Cymbalta

    https://www.sciencedirect.com/science/article/abs/pii/S0033318214001935?via%3Dihub https://doi.org/10.1016/j.psym.2014.12.003 Lesley Arnold, Thomas Blom, Jeffrey Welge, Elizabeth Mariutto, Alicia Heller Women’s Health Research Program, Department of Psychiatry and Behavioral Neuroscience...
    • Hutan
    • Thread
    • 2014 anti-depressant arnold cymbalta duloxetine me/cfs paper rct
    • Replies: 17
    • Forum: ME/CFS research
  18. Sly Saint

    Systematic review of randomized controlled trials for (CFS/ME) - Do-Young Kim et al Jan 2020

    Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) full paper https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-019-02196-9
    • Sly Saint
    • Thread
    • 2020 cortisol do-young kim korea me/cfs paper rct review systematic review treatment trial
    • Replies: 11
    • Forum: General ME/CFS news
  19. Sly Saint

    Psychosomatic therapy for patients frequently attending primary care with MUS,the CORPUS trial: study protocol for an RCT-Wortman et al 2019

    Psychosomatic therapy for patients frequently attending primary care with medically unexplained symptoms, the CORPUS trial: study protocol for a randomised controlled trial Open access, published Dec 2019 Trial status The protocol version number and date: version 10, 8 May 2018. Patient...
  20. Sly Saint

    Risk of bias tools in systematic reviews of health interventions: an analysis of PROSPERO-registered protocols - Farrah,Young,Tunis,Zhao Nov 2019

    full paper here https://systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-019-1172-8
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