Esther Crawley

Jonathan Edwards said:
I wonder what exactly is going on here. I have never previously come across the idea of doing a 'sort of' (or 'feasibility') study before, putatively, intending to do a proper study, other than the case of SMILE where it seems the sort of study turned out to be sort of the real study.

And I wonder what Dr Crawley, a paediatric rheumatologist, is doing as an author on a study of appendicitis? Is it that she is considered now to be an expert on sort of studies of this sort?
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I think its a way to avoid proper scrutiny from the ethics committee. I had assumed that phase 1 trials were effectively testing feasibility.

I did hear that Bristol Universities medical dept failed to get a 5 star rating and that Bristol has a habit of shutting non-five star rated departments. So I wonder if Crawley is well thought of because she is bringing in money and hence included (I assume she knows the right people on the MRC committees).
 
Adrian said:
I think its a way to avoid proper scrutiny from the ethics committee. I had assumed that phase 1 trials were effectively testing feasibility.

I did hear that Bristol Universities medical dept failed to get a 5 star rating and that Bristol has a habit of shutting non-five star rated departments. So I wonder if Crawley is well thought of because she is bringing in money and hence included (I assume she knows the right people on the MRC committees).
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"You may think that, but I couldn't possibly comment"

I think phase 1 studies tend to be done to make sure the treatment isn't terribly dangerous.
 
Jonathan Edwards said:
I thought you were going to ask how many psychologists it takes to change a light bulb.

The answer might be a bit subjective and more qualitative than quantitative.
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Did the lightbulbs have any issues during manufacture/ problematic delivery? Are there colour issues? Are they the right size..did they spend too long in storage without the chance of participating in serial or parallel switching? Too many questions before they come out of the box ....
 
strategist said:
Maybe Crawley has finally decided to useful work, after hitting her lowest point helping Phil Parker promote the lightning process?
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HAHAHAHAHAHHHHHHAAAAAA Crawley do useful work? What planet do you live on? (sorry) She'll continue to do whatever brings in the spondulicks and the possibility of a dame-hood. After all, Sir Simon made it to being knighted, so why not Lady Esther? :sick:
 
Amw66 said:
Did the lightbulbs have any issues during manufacture/ problematic delivery? Are there colour issues? Are they the right size..did they spend too long in storage without the chance of participating in serial or parallel switching? Too many questions before they come out of the box ....
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You can easily find out. Create a survey to hand to the psychologists that asks them what they think about it.
 
Sly Saint said:
Change of direction for Esther Crawley?

https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-018-2520-z
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Participants will be randomised into one of two arms. Participants in the intervention arm are treated with antibiotics and regular clinical assessment to ensure clinical improvement. Participants in the control arm will receive appendicectomy.
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What does this mean, antibiotics plus wishy washy buzz words?
I think placebos are more effective then buzzed words, though neither is a legitimate treatment for medical conditions. How ethical is this treatment anyways?
 
First they'd have to rename and redefine the lightbulb. Then they'd have to mix it in with a wide range of newly rechristened 'hanging electric items' for their high-quality, totally open-minded study into lightbulb changing.

While shouting 'STOP!' at the resultant assortment of lightbulbs, ceiling fans, extractor fans, and at least one or two ceiling-mounted speakers for good measure, they'd deduce that most 'lightbulbs' (as the hanging electric items themselves prefer to be called) in fact don't light up, but instead oscillate and move air.

They'd finally deduce that the hanging electric items suffer from 'false illumination beliefs' and would light up if only they tried a little harder. But they wouldn't share their workings with anyone and they'd change the goalposts from fitting the items to merely holding the objects up in the air.
 
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