brain

Full title: Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 Variants of Concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer’s disease Abstract COVID-19 and especially Long COVID are associated with severe CNS symptoms and may place persons...

Abstract Objective COVID-19 (SARS-CoV-2) has been associated with neurological sequelae even in those patients with mild respiratory symptoms. Patients experiencing cognitive symptoms such as “brain fog” and other neurologic sequelae for 8 or more weeks define “long haulers”. There is limited...

By Professor Tissa Wijeratne, University of Melbourne; Professor Meg Morris, La Trobe University; Associate Professor Leila Karimi, RMIT University; and Chanith Wijeratne, Monash University https://pursuit.unimelb.edu.au/articles/what-we-now-know-about-long-covid-and-our-brains

A quantified comparison of cortical atlases on the basis of trait morphometricity Anna E. Fürtjes, James H. Cole, Baptiste Couvy-Duchesne, Stuart J. Ritchie Abstract Background Many different brain atlases exist that subdivide the human cortex into dozens or hundreds of regions-of-interest...

https://bmcresnotes.biomedcentral.com/articles/10.1186/1756-0500-7-370 Open access Luis Nacul, Dominic G O’Donovan, Eliana M Lacerda, Djordje Gveric, Kirstin Goldring, Alison Hall, Erinna Bowman & Derek Pheby Abstract Background Our aim, having previously investigated through a qualitative...

An old thread, but the idea of a post-mortem biobank is often discussed on the forum, and this study was linked in one such discussion. https://jcp.bmj.com/content/63/11/1032 Not open-access Sci-hub link: https://sci-hub.wf/10.1136/jcp.2010.082032 Abstract Background Myalgic...

Washington Post: Animalia Why this mammal eats its own brain — and why it could matter for you Dino Grandoni “It’s a crazy animal,” said Dechmann, a behavioral ecologist at the Max Planck Institute of Animal Behavior in Germany. “We can learn a lot from the shrews.” To prepare for the depths...

Preprint See post 5 for published version Molecular and cellular similarities in the brain of SARS-CoV-2 and Alzheimer’s disease individuals Elizabeth Griggs, Kyle Trageser, Sean Naughton, Eun-Jeong Yang, Brian Mathew, Grace Van Hyfte, Linh Hellmers, Nathalie Jette, Molly Estill, Li Shen, Tracy...

A Case Report: Multifocal Necrotizing Encephalitis and Myocarditis after BNT162b2 mRNA Vaccination against COVID-19 Michael Mörz The current report presents the case of a 76-year-old man with Parkinson’s disease (PD) who died three weeks after receiving his third COVID-19 vaccination. The...

Pre Print: The pernicious danger of cortical brain maps Benjamin Yost Hayden The parcellation of the primate cerebral cortex into numbered regions, based on cytoarchitecture, began with the pioneering research of neuroanatomist Kobrinian Brodmann. While the borders between regions have...

Your Brain Is Not an Onion With a Tiny Reptile Inside Cesario, Johnson and Eisthen https://journals.sagepub.com/doi/full/10.1177/0963721420917687 full article free e pub Abstract A widespread misconception in much of psychology is that (a) as vertebrate animals evolved, “newer” brain...

Highlights Cognitive fatigue is explored with magnetic resonance spectroscopy during a workday Hard cognitive work leads to glutamate accumulation in the lateral prefrontal cortex The need for glutamate regulation reduces the control exerted over decision-making Reduced control favors the...

"The nervous and immune systems are tightly intertwined. Deciphering their chatter might help address many brain disorders and diseases." There is a lot more in the article about the brain, neuroimmunology, microglia, sickness behaviour, Alzheimer's, MS, etc, but this is the part that caught my...

COVID-19 Neuropathology: evidence for SARS-CoV-2 invasion of Human Brainstem Nuclei Aron Emmi, Stefania Rizzo, Luisa Barzon, Michele Sandre, Elisa Carturan, Alessandro Sinigaglia, Silvia Riccetti, Mila della Barbera, Rafael Boscolo-Berto, Patrizia Cocco, Veronica Macchi, Angelo Antonini, Monica...

Abstract Activation of innate immunity and deposition of blood-derived fibrin in the central nervous system (CNS) occur in autoimmune and neurodegenerative diseases, including multiple sclerosis (MS) and Alzheimer’s disease (AD). However, the mechanisms that link disruption of the blood–brain...

Neurovascular injury with complement activation and inflammation in COVID-19 Myoung-Hwa Lee, Daniel P. Perl, Joseph Steiner, Nicholas Pasternack, Wenxue Li, Dragan Maric, Farinaz Safavi, Iren Horkayne-Szakaly, Robert Jones, Michelle N. Stram, Joel T. Moncur, Marco Hefti, Rebecca D. Folkerth...

Abstract Background Fatigue is a common and burdensome symptom in Rheumatoid Arthritis (RA), yet is poorly understood. Currently, clinicians rely solely on fatigue questionnaires, which are inherently subjective measures. For the effective development of future therapies and stratification, it...

A recording of the 2022 Institute for Neuro-Immune Medicine (INIM) Conference, held on June 10, has been posted to YouTube.

Dr Nina Rzechorzek, MRC Clinician Scientist Fellow from the MRC Laboratory for Molecular Biology who led the study, said: “Using the most comprehensive exploration to date of normal human brain temperature, we’ve established ‘HEATWAVE’ – a 4D temperature map of the brain. This map provides an...

Abstract Background Among systemic abnormalities caused by the novel coronavirus, little is known about the critical attack on the central nervous system (CNS). Few studies have shown cerebrovascular pathologies that indicate CNS involvement in acute patients. However, replication studies are...