pem

  1. Sly Saint

    Understanding The Molecular Changes of Post Exertional Malaise In ME/CFS, 2021, Elley

    Abstract: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating and often life-long condition affecting over 20,000 New Zealanders. Symptoms include muscle and joint pain, severe fatigue, unrefreshing sleep, hypersensitivity to light and sound, and cognitive dysfunction...
  2. Sly Saint

    Network Analysis of Symptoms Co-Occurrence in Chronic Fatigue Syndrome, 2021, Kujawski, Staines,Newton et al

    Abstract Chronic fatigue syndrome (CFS) is a heterogenous disorder of multiple disabling symptoms with complex manifestations. Network analysis is a statistical and interrogative methodology to investigate the prevalence of symptoms (nodes) and their inter-dependent (inter-nodal) relationships...
  3. Hutan

    Chills

    For the last few days, I've been ending up in bed in the afternoons, unable to get warm, exhausted and feeling chills. I guess it's PEM, although it seems to just last a few hours and doesn't involve the body crushed pain that is my experience of full-on PEM. Chills are a frequent feature of...
  4. Sly Saint

    PEM - post exertional malaise very short video 2019

  5. Sly Saint

    Article: Will there ever be a test for chronic fatigue syndrome?

    rest of article here https://www.medicaldevice-network.com/features/cfs-me-test/
  6. Sly Saint

    Article in Verywell:Treating Post-Exertional Malaise in Chronic Fatigue Syndrome

    https://www.verywellhealth.com/managing-post-exertional-malaise-in-chronic-fatigue-716027
  7. cassava7

    PEM induced only by sensory/cognitive exertion - what does it indicate about the pathophysiology of ME?

    I read an account by a housebound ME patient about being able to handle very short car trips as a passenger, while longer ones flare their symptoms even though they remain as idle as possible. Such a flare could only plausibly be induced by sensory stimuli during the trip, among which vehicle...
  8. Sly Saint

    Gez Medinger videos: Part 1 Pacing - Ben Marsh, Part 2 GET - Todd Davenport et al.

    Video: Fatigue, Pacing and PEM Management | Lessons from ME/CFS - With Dr Ben Marsh I know this video has been mentioned on another thread but I think it might have been missed by many and deserves a thread of its own. In Episode 3 of our expert interviews series, Dr Asad Khan talks to Dr Ben...
  9. Sly Saint

    Chronic fatigue and post-exertional malaise in people living with long COVID, 2021 Twomey, DeMars et al

    Preprint Abstract Purpose: People living with long COVID describe a high symptom burden, and a more detailed assessment of chronic fatigue and post-exertional malaise (PEM) may inform the development of rehabilitation recommendations. The aims of this study were to use validated questionnaires...
  10. Nightsong

    Predicting post-exertional malaise in Gulf War Illness based on acute exercise responses (Boruch et al., 2021)

    Abstract Aims: Post-exertional malaise (PEM) is poorly understood in Gulf War Illness (GWI). Exercise challenges have emerged as stimuli to study PEM; however, little attention has been paid to unique cardiorespiratory and perceptual responses during exercise. This study tested whether select...
  11. Sly Saint

    Warning Signals of Post-Exertional Malaise in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Retrospective Analysis of 197 Patients, 2021, Ghali

    Abstract Post-exertional malaise (PEM), the key feature of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), is characterized by baseline symptom exacerbation after exposure to a stressor, and some patients can experience new or non-typical symptoms. We hypothesized that new or...
  12. Andy

    Post-Exertional Malaise ... Related to Central Blood Pressure, Sympathetic Activity and Mental Fatigue in [CFS] Patients, 2021, Kujawski, Newton et al

    Abstract Post-exertional malaise (PEM) is regarded as the hallmark symptom in chronic fatigue syndrome (CFS). The aim of the current study is to explore differences in CFS patients with and without PEM in indicators of aortic stiffness, autonomic nervous system function, and severity of...
  13. Sly Saint

    Blog: Since Being Diagnosed with Rheumatoid Arthritis, I Always Feel Like I Have the Flu. Here’s What I’ve Learned About Malaise.

    https://creakyjoints.org/about-arthritis/rheumatoid-arthritis/ra-patient-perspectives/what-malaise-feels-like-rheumatoid-arthritis/ (I had not seen this decription used in relation to RA before. It reads more like an ME patient)
  14. ME/CFS Science Blog

    Dissecting the nature of post-exertional malaise, Hartle et al, 2021

    Background Post-exertional malaise (PEM) is a defining characteristic of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) but there is insufficient research dissecting the nature of PEM from the patients’ perspective. Methods A PEM questionnaire administered to 150 ME/CFS patients...
  15. John Mac

    Open The Influence of Epigenetic Modifications and Post-Exertional Malaise in People With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 2021 Polli

    Not yet recruiting https://www.medifind.com/conditions/chronic-fatigue-syndrome/1135/clinical-trial/223304133
  16. Sly Saint

    Effects of Post-Exertional Malaise on Markers of Arterial Stiffness in Individuals with ME/CFS, Bond et al, 2021

    Effects of Post-Exertional Malaise on Markers of Arterial Stiffness in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome https://www.mdpi.com/1660-4601/18/5/2366/htm
  17. John Mac

    Open Analysis of Post-exertional Malaise Using a Two-day CPET in People With ME/CFS, 2021, Ithaca College

    https://www.centerwatch.com/clinical-trials/listings/225957/analysis-of-post-exertional-malaise-using-a-two-day-cpet-in-people-with-mecfs/?&radius=50&query=chronic-fatigue-syndrome&smt=true
  18. John Mac

    Exosome-associated Mitochondrial DNA is Elevated in Patients with ME/CFS and Stimulates Human Cultured Microglia to Secrete IL-1β, 2021, Theoharides

    https://www.researchsquare.com/article/rs-154011/v1
  19. John Mac

    Modulatory effects of cognitive exertion on regional functional connectivity of the salience network in women with ME/CFS: A pilot study, 2021, Manca

    https://www.jns-journal.com/article/S0022-510X(21)00019-8/fulltext
  20. Snow Leopard

    PEM: Swimming compared to other activities?

    In another thread, I noted that swimming leads to a difference balance in motor unit recruitment compared to land based activities and tends to favour a much greater rate of oxygen consumption for a given heart rate. I was not much of a swimmer when I was young and haven't picked it up since as...
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