pem

https://www.centerwatch.com/clinical-trials/listings/225957/analysis-of-post-exertional-malaise-using-a-two-day-cpet-in-people-with-mecfs/?&radius=50&query=chronic-fatigue-syndrome&smt=true

https://www.researchsquare.com/article/rs-154011/v1

https://www.jns-journal.com/article/S0022-510X(21)00019-8/fulltext

In another thread, I noted that swimming leads to a difference balance in motor unit recruitment compared to land based activities and tends to favour a much greater rate of oxygen consumption for a given heart rate. I was not much of a swimmer when I was young and haven't picked it up since as...

https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-020-02683-4

https://www.mdpi.com/2077-0383/9/12/4040/htm

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703497/

PEM has become a mandatory symptom in many CFS guidelines, so I would expect that there is plenty of data of monitored patients during the malaise/fatigue interval because this is when the disease's mechanism of action is amplified and certain biomarkers should stick out and be clearer. Maybe...

https://www.tandfonline.com/doi/abs/10.1080/21641846.2020.1845287

I have spent some time (probably far too much for my health) drafting and redrafting this letter with some helpful suggestions from members on a members only thread: https://www.s4me.info/threads/draft-letter-to-the-authors-of-the-nih-pem-study-2020.17052/ The letter refers to a paper discussed...

A couple of years ago I discovered that cumin (cuminum cyminum) was very effective at blocking my physically-induced PEM (didn't affect cerebrally-induced PEM). A level tsp of ground cumin would completely block PEM for 3 days. If I forgot my dose, and PEM started, taking cumin then would...

Full poll question: Please compare your typical PEM from physical overexertion with your typical PEM from cognitive overexertion. Consider the typical range of symptoms you get in each case, plus their timing and severity. Do you feel both types of PEM are fundamentally the same process or do...

Barbara Stussman1*, Ashley Williams2, Joseph Snow3, Angelique Gavin4, Remle Scott1, Avindra Nath4 and Brian Walitt5 Abstract Background: Myalgic encephalomyelitis/chronic fatigue syndrome is characterized by persistent and disabling fatigue, exercise intolerance, cognitive difficulty, and...

Factors Affecting the Characterization of Post-Exertional Malaise Derived from Patient Input https://digitalscholarship.unlv.edu/jhdrp/vol13/iss2/5/ (This would normally fit in research but is neither psychosocial nor biomedical, perhaps a category for research on clinical care is needed?)

The other day, my caree suggested that there might be a link between over-exertion (in this case, a phone conversation with a friend, I think) and excessive sweating. Has anyone else had any experience of this?

Just wondering if that is something others experience as well? Has the effect of exertion on water balance or relevant hormones in ME/CFS ever been studied?

Moderator note: This post has been copied and following posts moved from this thread: Epidemiological and clinical factors associated with post-exertional malaise severity in patients with ME/CFS. Ghali et al. 2020 ____________________ PEM studies always catch my attention, especially ones...

Paywall, https://content.iospress.com/articles/work/wor203168 Sci hub, https://sci-hub.tw/10.3233/WOR-203168

Several threads have been merged ME-conferences in Sweden Oct 17th and 18th 2018 RME, the Swedish patient organisation, invites once again to two conferences about ME this autumn. Some of the programme is in English, and some in Swedish. (I have translated the Swedish parts for this post)...

Sponsor Vrije Universiteit Brussel Overall contact Andrea Polli, MSc full details here: https://www.smartpatients.com/trials/NCT04378634