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Covid-19 vaccines and vaccinations

Discussion in 'Epidemics (including Covid-19, not Long Covid)' started by hinterland, Dec 3, 2020.

  1. Snow Leopard

    Snow Leopard Senior Member (Voting Rights)

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    The speculated mechanism proposed by Professor Michael Lunn is nonsense, it is not "molecular mimcry". In fact several studies (and most likely the vaccine manufacturers themselves) have already compared the genetic sequences and found there are no matching sequences of sufficient length. Secondly, GBS is mediated in a majority of cases by antibodies against gangliosides or ganglioside complexes, which are glycolypids not peptides.

    The most likely mechanism that explains all of the possible triggers of GBS is B-cell cocapture (Campylobacter Jejuni is a special case). Both the SARS-CoV-2 spike protein and the adenovirus capsid have been shown to bind to gangliosides (through sialic acid binding). The key point is the B-cell is autoreactive to self components (the gangliosides), but presents non-self peptides on MHC receptors to T-cells. (Also notably glycolipids aren't presented on MHC, there is a separate mechanism (CD1))

    But one of the risk factors of the AZ vaccine (also for the thrombosis and thrombocytopenia syndromes) is the fact that the vector is more stable (than mRNA vaccines) and therefore is able to circulate to tissue other than the lymph near the muscle, which can hypothetically increase the risk of the B-cell cocapture process occurring.

    The other factor when considering excess cases in whole populations is the underlying virus itself can trigger GBS, so if a vaccine has lower efficacy at preventing infections (compared to an alternative vaccine), it's also less likely to prevent GBS cases due to the virus itself.
     
    Amw66, FMMM1, Lilas and 7 others like this.
  2. TrixieStix

    TrixieStix Senior Member (Voting Rights)

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    Evidence that Original Antigenic Sin is indeed rearing it's ugly head? (The study only looked at people who have been vaccinated)

    "Previously infection-naïve HCW who became infected during the B.1.1.529 wave showed enhanced immunity against earlier variants, but reduced nAb potency and T cell responses against B.1.1.529 itself."

    https://www.science.org/doi/10.1126/science.abq1841
     
    Snow Leopard, Mij, Sean and 1 other person like this.
  3. Mij

    Mij Senior Member (Voting Rights)

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    I got a call for my 4th and I declined. I think I'll wait until the fall b/c I heard that the vaccine will include more variants? The nurse said she has no knowledge of this. Dunno.
     
    MeSci, Snow Leopard, Binkie4 and 4 others like this.
  4. TigerLilea

    TigerLilea Senior Member (Voting Rights)

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    I got the call for my fourth shot last week but I also declined it. I'm would never have a mRNA vaccine again.
     
  5. Mij

    Mij Senior Member (Voting Rights)

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    @TigerLilea

    How are you feeling now? Better I hope.
     
    MeSci, AliceLily, TigerLilea and 2 others like this.
  6. Mij

    Mij Senior Member (Voting Rights)

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    My sister arrives next week after a 16hr flight. She's self-isolating at an Airbnb for 3 days, bringing rapid tests, wears N95 mask and she's had 4 jabs. My jab appt would have been booked for July 15, it takes 2 weeks to build the antibodies and she'll be gone by then so no need for the 4th.
     
    MeSci, AliceLily and Binkie4 like this.
  7. Binkie4

    Binkie4 Senior Member (Voting Rights)

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    I have not had a fourth, and intend to refuse further vaccines until there is more understanding of the damage it can cause.
     
  8. Wonko

    Wonko Senior Member (Voting Rights)

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    I haven't been offered a fourth, despite being a priority for the third, which I seem to remember was late October.
     
  9. TigerLilea

    TigerLilea Senior Member (Voting Rights)

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    Unfortunately, I'm worse now than I was before. It's affecting my eyes and my hearing at the moment. :(
     
  10. TigerLilea

    TigerLilea Senior Member (Voting Rights)

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    I read something a few weeks ago that no one knows at what point we 'over' vaccinate and start causing damage to the immune system. This doctor was saying we can't continually keep vaccinating people against covid, at least not as often as we are at the moment.
     
  11. Trish

    Trish Moderator Staff Member

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    Hard to hit 'like' on your post. Really sorry to hear it's getting worse.
     
    Lilas, Wits_End, MeSci and 7 others like this.
  12. TigerLilea

    TigerLilea Senior Member (Voting Rights)

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    Thanks, Trish! From talking with people in the US who have seen neurologists, they are being told that adverse reactions to vaccines usually clear up anywhere from 6 months to 2 years. I'm still hopeful that at some point things will get better. One person was told by their neurologist that he estimates that 60% of his new patients last year were all coming in complaining of the same problems since having the covid vaccine(s). A friend of my mom is having the same problem with her eyes and an eye exam didn't find anything wrong. This seems to be what other people are being told also who are having the same issue.
     
  13. Snow Leopard

    Snow Leopard Senior Member (Voting Rights)

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    Moderna is planning on supplying polyvalent vaccines at some stage.

    We'd already have them if the respective health authorities in each country actually demanded it.
     
  14. Mij

    Mij Senior Member (Voting Rights)

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    Binkie4 likes this.
  15. TigerLilea

    TigerLilea Senior Member (Voting Rights)

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    :emoji_anguished:
     
    mango likes this.
  16. rvallee

    rvallee Senior Member (Voting Rights)

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    Thanks to medicine completely screwing up everything about the pandemic, the window for vaccines is closed. I genuinely fear what this would mean if a more serious pandemic occurred any time soon that could kill hundreds of millions. Especially the weird obsession with saying "this is not the flu", minimizing the flu, even though it's a serious disease and the main danger with Covid is that it's far more infectious, multiplies the same harm by sheer numbers.

    Almost every time I've heard infectious disease specialists talk about what keeps them up at night, it's a flu pandemic. Then again, they have been collectively wrong about so many things that maybe they're wrong about that, too, are simply extrapolating from the 1918 pandemic as THE big one so can only think within this box.

    All mostly because of the need to continue denying Long Covid. While medicine dismisses, even openly mocks, the idea that this is a serious issue, what the conspiracy crowds are doing is attributing it all to the vaccines. And it's working extremely well. Just look at this twitter thread below, they're having a field day and you can bet that everyone with undiagnosed mild, or moderate, Long Covid who has no explanation for their bizarre symptoms are going to attribute them all to the vaccines, made significantly worse by being told it's in their imagination in a condescending manner. It may be part true that vaccines cause some of those illnesses, or more precisely the immune system's reaction, but the stubborn refusal to study it, on the basis of belief in mass hysteria and how fear is worse than illness, means we won't know in time to make a difference.

    https://twitter.com/user/status/1544445581623541765


    But vaccines will not be part of the solution moving forward. Too many people will refuse them to work, we've actually lost this tool for the near future. It won't be possible to mandate them because of all the damn politics. Vaccine refusal will likely grow significantly, all the vaccines, all thanks to medicine and their belief in the BPS ideology. Because they play politics but are terrible at it. They're relying on biopsychosocial ideology to guide their model of how people react to illness, and their models of fear and anxiety and whatever. They're playing politics with literal caricatures of human behavior to guide them. No profession has screwed up this hard in at least a century. Being this bad at politics only works by force, by imposition, by dictatorship. Trust is necessary in public health, and it's been fully destroyed for a generation.

    Because meanwhile the minimizers keep minimizing, no matter how many times they're wrong. And they still tut-tut the people looking at the possible worse-case, not worst, just worse, scenarios. The serially-wrong minimizers are never criticized for minimizing, only the people who warn accurately are being admonished for being Debbie Downers, all based on medicine's obsession with stress and anxiety being the main explanation for all illness and a giant hit from the hopium bong.

    Humanity has never been failed worse by experts. It's remarkable to live through this. All because of dumb 19th century beliefs, of all things. What a great filter this is.
     
  17. Mij

    Mij Senior Member (Voting Rights)

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  18. Sarah

    Sarah Senior Member (Voting Rights)

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    A 13 minute video by Dr John Campbell on German vaccine safety data from Paul Ehrlich Institut report, Safety of COVID-19 Vaccines.

    https://www.youtube.com/watch?v=XlGXFRs4ZOA



    Campbell acknowledges temporal link does not necessarily mean causation but also suggests not all adverse events would have been reported or recognised as such.

    Link to the English language version of the report:
    https://www.pei.de/EN/newsroom/dossier/coronavirus/medicine-safety.html
     
    Binkie4 and Trish like this.
  19. Dakota15

    Dakota15 Senior Member (Voting Rights)

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    This vaccine situation has been a disaster all the way around. So many adverse reactions with little help to patients. So much trust dissipated with medical system in general.
     
    Binkie4 likes this.
  20. Trish

    Trish Moderator Staff Member

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    I don't understand your logic, @Dakota15. There is plenty of evidence worldwide that Covid-19 vaccinations have greatly reduced the rate of death and serious illness from Covid-19.

    Of course those suffering symptoms following vaccination should be given appropriate medical support, but the numbers in that situation are far outweighed by lives saved by the vaccines.
     
    Hutan, Nellie, Peter Trewhitt and 5 others like this.

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